Results 11 to 20 of about 532,604 (238)

Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues

open access: yesScientific Reports, 2021
Colorectal cancer (CRC) is a major cancer, and its precise diagnosis is especially important for the development of effective therapeutics. In a series of metabolome analyses, the levels of very long chain fatty acids (VLCFA) were shown to be elevated in
Kotaro Hama   +7 more
doaj   +2 more sources

Nonesterified Fatty Acids, Albumin, and Platelet Aggregation [PDF]

open access: yesDiabetes, 2015
It has been known for five decades that nonesterified fatty acids (NEFAs) have a role in the activation of platelets and thrombosis. Thus, the infusion of NEFAs leads to massive thrombosis and platelet activation (1–4). It has also been shown that their binding to albumin protects the platelets from activation (5).
Sandeep Dhindsa   +2 more
openaire   +4 more sources

Fasting and Postload Nonesterified Fatty Acids and Glucose Dysregulation in Older Adults. [PDF]

open access: greenAm J Epidemiol, 2022
Shitole SG   +8 more
europepmc   +3 more sources

Serum Individual Nonesterified Fatty Acids and Risk of Heart Failure in Older Adults. [PDF]

open access: yesCardiology, 2021
Background: Heart failure (HF) is highly prevalent among older adults and is associated with high costs. Although serum total nonesterified fatty acids (NEFAs) have been positively associated with HF risk, the contribution of each individual NEFA to HF ...
Djousse L   +11 more
europepmc   +2 more sources

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan   +22 more
wiley   +1 more source

Nonesterified fatty acids and cardiovascular mortality in elderly men with CKD.

open access: yesClin J Am Soc Nephrol, 2015
BACKGROUND AND OBJECTIVES Although nonesterified fatty acids (NEFAs) are essential as energy substrate for the myocardium, an excess of circulating NEFAs can be harmful.
Xiong Z   +9 more
europepmc   +2 more sources

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