Results 21 to 30 of about 532,604 (238)

Substrate modulation of fatty acid effects on energization and respiration of kidney proximal tubules during hypoxia/reoxygenation. [PDF]

PLoS ONE, 2014
Kidney proximal tubules subjected to hypoxia/reoxygenation develop a nonesterified fatty acid-induced energetic deficit characterized by persistent partial mitochondrial deenergization that can be prevented and reversed by citric acid cycle substrates ...
Anja Bienholz, Ahmad Al-Taweel, Nancy F Roeser, Andreas Kribben, Thorsten Feldkamp, Joel M Weinberg   +5 more
doaj   +1 more source

Regulation of Insulin Clearance by Non-Esterified Fatty Acids

Biomedicines, 2022
Insulin stores lipid in adipocytes and prevents lipolysis and the release of non-esterified fatty acids (NEFA). Excessive release of NEFA during sustained energy supply and increase in abdominal adiposity trigger systemic insulin resistance, including in
Sonia M. Najjar, Raziyeh Abdolahipour, Hilda E. Ghadieh, Marziyeh Salehi Jahromi, John A. Najjar, Basil A. M. Abuamreh, Sobia Zaidi, Sivarajan Kumarasamy, Harrison T. Muturi   +8 more
doaj   +1 more source

Heritability estimates of predicted blood β-hydroxybutyrate and nonesterified fatty acids and relationships with milk traits in early-lactation Holstein cows.

Journal of Dairy Science, 2020
At the beginning of lactation, high-producing cows commonly experience an unbalanced energy status that is often responsible for the onset of metabolic disorders and impaired health and performance.
A. Benedet, A. Costa, M. Marchi, M. Penasa   +3 more
semanticscholar   +1 more source

Sirtuin 3 improves fatty acid metabolism in response to high nonesterified fatty acids in calf hepatocytes by modulating gene expression.

Journal of Dairy Science, 2020
Sirtuin 3 (SIRT3), a mitochondrial deacetylase, is a key regulator of energy metabolism in the liver. In nonruminants, the hepatic abundance of SIRT3 is decreased in individuals with nonalcoholic fatty liver diseases, and recovery of SIRT3 alleviates ...
Leihong Liu, D. Xing, Xiliang Du, Tao Peng, J. McFadden, L. Wen, Hongyu Lei, W. Dong, Guowen Liu, Zhe Wang, Jianming Su, Jianhua He, Xinwei Li   +12 more
semanticscholar   +1 more source

Perceptual Quality of Nonesterified Fatty Acids Varies with Fatty Acid Chain Length

Chemical Senses, 2021
Abstract Nonesterified fatty acids (NEFA) are effective taste stimuli. The quality they impart has not been well characterized. Sourness, and “fattiness” have been reported, but an irritation component has also been described and how these transition with gradations of aliphatic chain length has not been systematically studied.
Eunjin Cheon, Richard D Mattes
openaire   +3 more sources

Use of milk fatty acids to estimate plasma nonesterified fatty acid concentrations as an indicator of animal energy balance.

Journal of Dairy Science, 2017
Negative energy balance is an important part of the lactation cycle, and measuring the current energy balance of a cow is useful in both applied and research settings. The objectives of this study were (1) to determine if milk fatty acid (FA) proportions
J. Dórea, E. French, L. Armentano
semanticscholar   +1 more source

The Role of TCA Cycle Anaplerosis in Ketosis and Fatty Liver in Periparturient Dairy Cows

Animals, 2015
The transition to lactation period in dairy cattle is characterized by metabolic challenges, negative energy balance, and adipose tissue mobilization. Metabolism of mobilized adipose tissue is part of the adaptive response to negative energy balance in ...
Heather M. White
doaj   +1 more source

Metabolic, inflammatory, and oxidative stress markers in women exposed to secondhand smoke [PDF]

PeerJ, 2018
Background Secondhand smoke (SHS) exposure has adverse effects on the cardiovascular system. This study aimed to determine the effects of SHS on the cardiovascular disease biomarkers, namely the metabolic, inflammatory, and oxidative stress markers in ...
Mohd Hanaffi Siti Hajar, Sanip Zulkefli, Shaaban Juwita, Mohd Noor Norhayati, Mohd Yusoff Siti Suhaila, Aida Hanum Ghulam Rasool, Mohamed Yusoff Harmy   +6 more
doaj   +2 more sources

Non-esterified fatty acids in the ovary: friends or foes?

Reproductive Biology and Endocrinology, 2020
A majority of common metabolic diseases can result in excessive lipolysis, leading to elevated levels of non-esterified fatty acids (NEFAs) in the body fluids.
Vijay Simha Baddela, Arpna Sharma, Jens Vanselow   +2 more
doaj   +1 more source

Short communication: Association of milk fatty acids with early lactation hyperketonemia and elevated concentration of nonesterified fatty acids.

Journal of Dairy Science, 2016
The objective of our study was to extend the limited research available on the association between concentrations of milk fatty acids and elevated nonesterified fatty acids (NEFA) and β-hydroxybutyrate (BHB) concentrations in early lactation dairy cattle.
S. Mann, D. Nydam, A. Lock, T. Overton, J. McArt   +4 more
semanticscholar   +1 more source