Results 71 to 80 of about 5,756 (191)
Sulfur-Containing Compounds from Endophytic Fungi: Sources, Structures and Bioactivities
Journal of Fungi, 2022 Endophytic fungi have attracted increasing attention as an under-explored source for the discovery and development of structurally and functionally diverse secondary metabolites.
Yaqin Fan +6 more
doaj +1 more source
Plastic Diets Drive Microbiome and Metabolic Reprogramming in Wax Moth Larvae (Achroia grisella)
Archives of Insect Biochemistry and Physiology, Volume 122, Issue 3, July 2026.Wax moth larvae (Achroia grisella) can consume LDPE and PLA, triggering polymer‐specific restructuring of the gut microbiome and host metabolism. LDPE feeding enriches Bacillus spp. and is associated with shifts in carbohydrate and amino‐acid pathways consistent with hydrocarbon processing, whereas PLA feeding enriches Enterococcus spp.
Rohan Shah +9 more
wiley +1 more source
Reprogramming Promiscuous Nonribosomal Peptide Synthetases for Production of Specific Peptides
, 2019 Pairs of docking domains (DDs) mediate the selective interations between adjacent nonribosomal peptide synthetases (NRPSs) to form defined protein–protein interactions resulting in defined peptide sequences.
Bode, H. +5 more
core +1 more source
Crystal Structure and Conformational Dynamics of N─N Bond‐Forming Piperazate Synthase
ChemBioChem, Volume 27, Issue 12, 26 June 2026.Piperazate synthases (PZSs) catalyze the key N─N bond formation in the biosynthesis of the rare amino acid piperazic acid. X‐ray crystal structures of apo‐ and holo‐SbPZS show a dimeric enzyme with two heme‐containing active sites, where histidine residues coordinate the iron centers.
Nikita Pal +7 more
wiley +1 more source
, 2022 A chemical investigation of Aspergillus californicus IBT 16748 led to the isolation of two new oxepine-pyrimidinone-ketopiperazine type nonribosomal peptides oxepinamides L (1) and M (2).
Larsen, Thomas O. +8 more
core +1 more source
Structural Biology of Nonribosomal Peptide Synthetases [PDF]
, 2016 The nonribosomal peptide synthetases are modular enzymes that catalyze synthesis of important peptide products from a variety of standard and non-proteinogenic amino acid substrates. Within a single module are multiple catalytic domains that are responsible for incorporation of a single residue. After the amino acid is activated and covalently attached
Bradley R, Miller, Andrew M, Gulick
openaire +2 more sources
Marine Drugs, 2022 Cinnamoyl-containing nonribosomal peptides (CCNPs) form a unique family of actinobacterial secondary metabolites and display various biological activities.
Sangwook Kang +10 more
doaj +1 more source
Chemistry – A European Journal, Volume 32, Issue 24, 23 June 2026.This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami +2 more
wiley +1 more source
Chapter 14 Biosynthesis of Nonribosomal Peptide Precursors
, 2009 Nonribosomal peptides are natural products typically of bacterial and fungal origin. These highly complex molecules display a broad spectrum of biological activities, and have been exploited for the development of immunosuppressant, antibiotic ...
Wilkinson, Barrie +3 more
core +1 more source
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2013 The third part of the review is concerned with investigation of nonribosomal peptides.
T. I. Orlova +2 more
openaire +2 more sources