Results 111 to 120 of about 3,421,850 (195)
, 2009 BACKGROUND/AIMS: The nonstructural 5A (NS5A) protein of hepatitis C virus (HCV) has been implicated in HCV-induced liver pathogenesis. Wnt/beta-catenin signaling has also been involved in tumorigenesis.
김호근
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Characterisation of the membrane and protein interactions of the Hepatitis C Virus NS2 [PDF]
, 2011 Hepatitis C virus (HCV) readily establishes a chronic infection and it is currently thought to infect 2-3% of the global population. Treatment for HCV places a severe burden on patients, leading to a premature treatment termination in approximately 20 ...
King, Barnabas James
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Hepatology Communications, 2017 Concomitant proton pump inhibitor (PPI) use reduces plasma concentrations of certain nonstructural protein 5A inhibitors, which are key components of modern hepatitis C infection (HCV) treatments.
Nancy Reau +9 more
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PLoS Pathogens, 2013 The lipid kinase phosphatidylinositol 4-kinase III alpha (PI4KIIIα) is an essential host factor of hepatitis C virus (HCV) replication. PI4KIIIα catalyzes the synthesis of phosphatidylinositol 4-phosphate (PI4P) accumulating in HCV replicating cells due ...
Simon Reiss +8 more
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Daclatasvir: potential role in hepatitis C
Drug Design, Development and Therapy, 2013 Choongho Lee College of Pharmacy, Dongguk University-Seoul, Goyang, Republic of Korea Abstract: Chronic hepatitis C virus (HCV) infection is responsible for the development of liver cirrhosis and hepatocellular carcinoma.
Lee C
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PLoS Pathogens, 2015 Many positive-strand RNA viruses encode genes that can function in trans, whereas other genes are required in cis for genome replication. The mechanisms underlying trans- and cis-preferences are not fully understood.
Teymur Kazakov +5 more
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Studying protein-protein interactions using peptide arrays [PDF]
, 2010 Screening of arrays and libraries of compounds is well-established as a high-throughput method for detecting and analyzing interactions in both biological and chemical systems. Arrays and libraries can be composed from various types of molecules, ranging
Rito, T. +7 more
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Drug Design, Development and Therapy, 2018 Kenichi Morikawa, Akihisa Nakamura, Tomoe Shimazaki, Naoya Sakamoto Department of Gastroenterology and Hepatology, Hokkaido University Faculty of Medicine and Graduate School of Medicine, Sapporo, Japan Abstract: Treatments for hepatitis C virus (HCV ...
Morikawa K +3 more
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HIV glycoprotein envelope; nonstructural protein 5A (NS5A); C5A [PDF]
Science-Business eXchange, 2008 openaire +1 more source
Elbasvir/Grazoprevir for HCV Infection in Russia: A Randomized Trial
Hepatic Medicine: Evidence and Research, 2020 Konstantin Zhdanov,1 Vasily Isakov,2 Eduard Burnevich,3 Svetlana Kizhlo,4 Igor Bakulin,5 Vadim Pokrovsky,6 Liwen Liang,7 Peggy Hwang,7 Rohit Talwani,7 Barbara A Haber,7 Michael N Robertson7 1Military Medical Academy n.a. S.M. Kirov, St.
Zhdanov K +10 more
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