European Journal of Immunology, Volume 56, Issue 2, February 2026.We developed murine CMV‐based viral vectors expressing SARS‐CoV‐2 spike antigen and compared immune response following intraperitoneal and intranasal delivery. Route of vaccine administration shaped antibody and CD8+ T cell response magnitude, kinetics, and tissue residency, highlighting the potential of CMV vectors for induction of protective lung ...
Maja Cokarić Brdovčak +9 more
wiley +1 more source
An acidic region of the 89K murine cytomegalovirus immediate early protein interacts with DNA [PDF]
, 1992 The product of the ie 1 gene, the regulatory immediate early protein pp89 of murine cytomegalovirus (MCMV), interacts with core histones, which can mediate the association of pp89 with DNA.
Koszinowski, Ulrich H. +3 more
core +1 more source
PLoS ONE, 2012 Hepatitis C virus (HCV) infects B lymphocytes and induces mixed cryoglobulinemia and B cell non-Hodgkin's lymphoma. The molecular mechanism for the pathogenesis of HCV infection-mediated B cell disorders remains obscure. To identify the possible role for
Kenji Nakashima +8 more
doaj +1 more source
Hepatitis C Virus Nonstructural Protein 5A Interacts with Immunomodulatory Kinase IKKε to Negatively Regulate Innate Antiviral Immunity. [PDF]
Mol Cells, 2022 Kang SM +6 more
europepmc +1 more source
Genetic analysis of members of the species Oropouche virus and identification of a novel M segment sequence [PDF]
, 2015 Oropouche virus (OROV) is a public health threat in South America, and in particular Northern Brazil, causing frequent outbreaks of febrile illness.
Azevedo, Raimunda S.S. +8 more
core +1 more source
Expression and function of osteopontin variants in HCV-related liver disease and hepatocellular carcinoma. [PDF]
, 2010 Osteopontin (OPN) is a highly secreted multi-functional sialoprotein that is widely expressed in tissues, blood and urine. It is involved in a number of normal physiological functions, but is also significantly elevated in a number of cancers.
Phillips, Renee Jade
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Drosophila CG3303 is an essential endoribonuclease linked to TDP-43-mediated neurodegeneration [PDF]
, 2017 Endoribonucleases participate in almost every step of eukaryotic RNA metabolism, acting either as degradative or biosynthetic enzymes. We previously identified the founding member of the Eukaryotic EndoU ribonuclease family, whose components display ...
BOZZONI, Irene +11 more
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Innate immune basis for rift valley fever susceptibility in mouse models [PDF]
, 2017 Rift Valley fever virus (RVFV) leads to varied clinical manifestations in animals and in humans that range from moderate fever to fatal illness, suggesting that host immune responses are important determinants of the disease severity. We investigated the
Bruhns, Pierre +7 more
core +3 more sources
BMC Gastroenterology, 2012 Background The aims of this study were to assess the prevalence of hepatitis C virus (HCV) infection in Japanese patients with oral lichen planus and identify the impact of amino acid (aa) substitutions in the HCV core region and IFN-sensitivity ...
Nagao Yumiko, Sata Michio
doaj +1 more source
Ultrastructure of Kunjin virus-infected cells: Colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structures [PDF]
, 1997 The subcellular location of the nonstructural proteins NS1, NS2B, and NS3 in Vero cells infected with the flavivirus Kunjin was investigated using indirect immunofluorescence and cryoimmunoelectron microscopy with monospecific antibodies, Comparisons ...
Westaway, Edwin G. +4 more
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