Interventional therapies for chronic heart failure: An overview of recent developments
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo +7 more
wiley +1 more source
Possible mechanisms underlying the midazolam‐induced relaxation of the noradrenaline‐contraction in rabbit mesenteric resistance artery [PDF]
Yoshihisa Shiraishi +5 more
openalex +1 more source
Abstract Aims Mortality in cardiogenic shock (CS) remains elevated, with the potential for CS causes to impact prognosis and risk stratification. The aim was to investigate in‐hospital prognosis and mortality in CS patients according to aetiology. We also assessed the prognostic accuracy of CardShock and IABP‐SHOCK II scores.
Cosme García‐García +17 more
wiley +1 more source
Effects of amphetamine derivatives on brain dopamine and noradrenaline [PDF]
George R. Breese +2 more
openalex +1 more source
Mid‐term survival in patients awaiting heart and kidney transplantation with Impella 5.5 support
Abstract Background Patients with end‐stage heart failure and chronic kidney disease requiring dual‐organ transplantation (DOT) face significant challenges in utilizing durable mechanical circulatory support due to the risks associated with renal replacement therapies (RRTs) and multi‐organ failure.
Smruti Desai +12 more
wiley +1 more source
Comparison of the effects of nadolol and bisoprolol on noradrenaline‐evoked venoconstriction in man in vivo [PDF]
A. H. Abdelmawla +3 more
openalex +1 more source
The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori +9 more
wiley +1 more source
Worsening versus advanced heart failure: Management and challenges
Clinical feature, circulating biomarkers and therapeutic management of patients with WHF versus AdvHF. Abbreviations: AdvHF, advanced heart failure; HF, heart failure; HTx, heart transplant; GDMT, guideline‐directed medical therapy; MCS, mechanical circulatory support; NYHA, New York Heart Association; WHF, worsening heart failure.
Alberto Palazzuoli +15 more
wiley +1 more source
Patients with AMI‐CS (lactate >3 mmol/L) enrolled in the multicentre, randomized ECLS‐SHOCK trial were included. From a total of 417 patients, 51.6% (n = 215), 13.4% (n = 56) and 35.0% (n = 146) presented in SCAI Stages C, D and E, respectively. SCAI stages were associated with the risk of 30 day all‐cause mortality, with rates of renal replacement ...
Janine Pöss +13 more
wiley +1 more source
The acute effect of insulin on heart rate, blood pressure, plasma noradrenaline and urinary albumin excretion [PDF]
Carl Erik Mogensen +2 more
openalex +1 more source

