Results 51 to 60 of about 138,491 (253)
Parkinson’s disease (PD) is a neurodegenerative disease with both motor and non-motor manifestations. Hyposmia is one of the early non-motor symptoms, which can precede motor symptoms by several years.
Christian Pifl +8 more
doaj +1 more source
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu +4 more
wiley +1 more source
The aim of present work is to assess the effects of bradykinin (Br) or noradrenaline (Nor) preconditioning to the levels of antioxidant enzymes: superoxide dismutase (SOD), copper, zinc superoxide dismutase (CuZn-SOD), manganese superoxide dismutase (Mn ...
Marianna Danková +5 more
doaj +1 more source
An Investigation of Sleep Macro‐ and Microarchitecture by APOE Genotype
Objectives Apolipoprotein E ε4 (APOE ε4), a robust genetic risk factor for Alzheimer's disease (AD) is associated with functional connectivity deficits and amyloid pathology in brain regions involved in sleep regulation. Thus, alterations in sleep architecture may be one pathway through which ε4 contributes to Alzheimer's disease vulnerability. However,
Gawon Cho +6 more
wiley +1 more source
Innervation of the bone marrow (BM) has been described more than one century ago, however the first in vivo evidence that sympathoadrenergic fibers have a role in hematopoiesis dates back to less than 25 years ago.
Marco eCosentino +2 more
doaj +1 more source
Increased Noradrenaline as an Additional Cerebrospinal Fluid Biomarker in PSP-Like Parkinsonism
Academic centers utilize sequential clinical and neuroimaging assessments, including morphometric ratios, to obtain an unequivocal diagnosis of the non-synucleinopathic forms of Parkinsonism, such as progressive supranuclear palsy (PSP), however, a 1–2 ...
Rocco Cerroni +9 more
doaj +1 more source
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl +10 more
wiley +1 more source
Noradrenergic and cholinergic modulation of olfactory bulb sensory processing
Neuromodulation in sensory perception serves important functions such as regulation of signal to noise ratio, attention, and modulation of learning and memory.
Christiane eLinster, Sasha eDevore
doaj +1 more source
Synthese von Aminocyclopropanen durch redoxneutrale Aminoalkylierung
Wir berichten über eine Synthese von Aminocyclopropanen durch Hydroaminoalkylierung unter Einsatz kostengünstiger, leicht zugänglicher Ausgangsmaterialien. Der Ansatz bietet Orthogonalität zu gängigen Methoden und ermöglicht eine breite Toleranz gegenüber funktionellen Gruppen.
Gwyndaf A. Oliver +6 more
wiley +1 more source
BackgroundThe present study was designed to evaluate the preconditioning effect of different doses of noradrenaline on ischemia-induced ventricular arrhythmias in open chest anesthetized rats.MethodsThe anaesthetized rats were subjected to 25 min of ...
Alireza Imani +4 more
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