Results 61 to 70 of about 138,491 (253)

Comparison of the Effects of Octopamine and Noradrenaline on Feeding and Sleep-like Behaviour in Fasted Chicks

open access: yesThe Journal of Poultry Science, 2002
Octopamine, an important neurotransmitter in invertebrates, has noted several similarities with noradrenaline (NA) in mammals. To compare the effect of octopamine and NA in the central nervous system, food intake and categorized postures of fasted chicks
Takashi Bungo   +3 more
doaj   +1 more source

Synthesis of Aminocyclopropanes by Redox‐Neutral Aminoalkylation

open access: yesAngewandte Chemie International Edition, EarlyView.
Aminocyclopropane synthesis by hydroaminoalkylation utilizing cheap, readily available starting materials is presented, offering orthogonality to commonly used methods and allowing broad functional‐group tolerance. Solvent‐mediated conditions enable the reaction of a pre‐formed hemiaminal with alkenes and alkynes.
Gwyndaf A. Oliver   +6 more
wiley   +1 more source

Pupil dilation signals uncertainty and surprise in a learning gambling task

open access: yesFrontiers in Behavioral Neuroscience, 2014
Pupil dilation under constant illumination is a physiological marker which modulation is related to several cognitive functions involved in daily decision making.
Claudio eLavin   +6 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

Hormonal and Psychological Responses to a Single Cold-Water Immersion in Regularly Winter-Swimming Males

open access: yesApplied Sciences
The psychological response to cold is complex. The present study aimed to determine if regular winter swimmers differed from those who did not practise winter swimming in terms of (1) daily perceived emotional states, (2) subjectively perceived ...
Aneta Teległów   +2 more
doaj   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou   +3 more
wiley   +1 more source

Monoaminergic System Modulation in Depression and Alzheimer’s Disease: A New Standpoint?

open access: yesFrontiers in Pharmacology, 2019
The prevalence of depression has dramatically increased, and it has been estimated that over 300 million people suffer from depression all over the world. Depression is highly comorbid with many central and peripheral disorders.
Maria Grazia Morgese, Luigia Trabace
doaj   +1 more source

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz   +7 more
wiley   +1 more source

Adrenergic signals influence proteomic responses in breast cancer cells

open access: yesFrontiers in Neuroscience
IntroductionBreast cancer remains a major health challenge due to its molecular heterogeneity and complex interactions with the tumor microenvironment.
Manuel Carrasco   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy