Results 71 to 80 of about 208,237 (324)

CARDIAC NORADRENALINE STORES [PDF]

British Journal of Pharmacology and Chemotherapy, 1963
The effects of single doses of reserpine or of guanethidine in increasing the heart rate of the dog heart‐lung preparation have been studied. Compared with reserpine, guanethidine increased heart rate more and more rapidly, and the increase lasted longer.
G, FAWAZ, J, SIMAAN
openaire   +2 more sources

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Bradykinin and noradrenaline preconditioning influences level of antioxidant enzymes SOD, CuZn-SOD, Mn-SOD and catalase in the white matter of spinal cord in rabbits after ischemia/reperfusion

European Journal of Histochemistry, 2019
The aim of present work is to assess the effects of bradykinin (Br) or noradrenaline (Nor) preconditioning to the levels of antioxidant enzymes: superoxide dismutase (SOD), copper, zinc superoxide dismutase (CuZn-SOD), manganese superoxide dismutase (Mn ...
Marianna Danková, Iveta Domoráková, Zuzana Fagová, Milan Stebnický, Alexandra Kunová, Eva Mechírová   +5 more
doaj   +1 more source

Noradrenaline and Parkinson's Disease [PDF]

Frontiers in Systems Neuroscience, 2011
Parkinson's disease (PD) is characterized by the degeneration of dopamine (DA) neurons in the substantia nigra pars compacta, and motor symptoms including bradykinesia, rigidity, and tremor at rest. These symptoms are exhibited when striatal dopamine concentration has decreased by around 70%.
Claire eDelaville, Philippe eDe Deurwaerdère, Abdelhamid eBenazzouz, Abdelhamid eBenazzouz   +3 more
openaire   +4 more sources

A Biomimetic Norepinephrine‐Loaded Aligned Mineralized Collagen Scaffold for Coordinated Neurovascular, Osteogenic, and Immunomodulatory Repair of Critical‐Sized Bone Defects

Advanced Science, EarlyView.
Inspired by the composition and structure of native bone tissue and its complex interplay of biological signals, a norepinephrine‐loaded biomimetic mineralized electrocompacted collagen scaffold (NE‐MEC) is developed capable of simultaneously supporting osteogenesis, neural repair, angiogenesis, and immune modulation.
Zhengyun Ren, Zhaojun Wu, Anhang Wu, Hui Zhang, Jiachen Lu, Jiahao Zhang, Jie Weng, Jinhua Zhang, Song Chen, Huan Tan, Tailin Guo   +10 more
wiley   +1 more source

SYMPATHOADRENERGIC MODULATION OF HEMATOPOIESIS: A REVIEW OF AVAILABLE EVIDENCE AND OF THERAPEUTIC PERSPECTIVES

Frontiers in Cellular Neuroscience, 2015
Innervation of the bone marrow (BM) has been described more than one century ago, however the first in vivo evidence that sympathoadrenergic fibers have a role in hematopoiesis dates back to less than 25 years ago.
Marco eCosentino, Franca eMarino, Georges J.M. Maestroni   +2 more
doaj   +1 more source

Noradrenergic projections from the locus coeruleus to the amygdala constrain fear memory reconsolidation

eLife, 2020
Memory reconsolidation is a fundamental plasticity process in the brain that allows established memories to be changed or erased. However, certain boundary conditions limit the parameters under which memories can be made plastic.
Josué Haubrich, Matteo Bernabo, Karim Nader   +2 more
doaj   +1 more source

All Nanozyme‐Based Cascade Reactions for Biomedical Applications: from Self‐Cascading Nanozyme to Immobilized Cascade Nanozyme

Advanced Science, EarlyView.
This review introduces the development and classification of all‐nanozyme cascade reaction systems, highlighting mechanistic insights and research methods for understanding catalytic features and design principles. It provides detailed classifications, surveys recent applications in biosensing and therapy, and discusses the challenges that all‐nanozyme
Caixia Zhu, Congcong Jiang, Hian Kee Lee, Yuanjian Zhang, Sheng Tang   +4 more
wiley   +1 more source

Noradrenergic and cholinergic modulation of olfactory bulb sensory processing

Frontiers in Behavioral Neuroscience, 2012
Neuromodulation in sensory perception serves important functions such as regulation of signal to noise ratio, attention, and modulation of learning and memory.
Christiane eLinster, Sasha eDevore
doaj   +1 more source

Biochemical and Genetic Studies of UBR3, a Ubiquitin Ligase with a Function in Olfactory and Other Sensory Systems [PDF]

, 2007
Our previous work identified E3 ubiquitin ligases, termed UBR1-UBR7, that contain the ~70-residue UBR box, a motif important for the targeting of N-end rule substrates.
Hellweg, Rainer, Hörtnagl, Heidi, Kwon, Yong Tae, Sohr, Reinhard, Tasaki, Takafumi, Varshavsky, Alexander, Xia, Zanxian   +6 more
core   +1 more source