Results 111 to 120 of about 1,694,370 (293)

300 degrees C operation of normally-off AlGaN/GaN MOSFET with low leakage current and high on/off current ratio [PDF]

open access: yes, 2014
300??C operation of a normally-off AlGaN/GaN metal-oxide semiconductor field-effect transistor (MOSFET) is successfully demonstrated, which is fabricated using a self-terminating gate recess etching technique.
Xu, Zhe   +13 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Normally-off m.e.s.f.e.t. with fast switching behaviour

open access: yesElectronics Letters, 1974
Normally-off m.c.s.f.e.t.s, fabricated on an insulating GaAs substrate with a vapour-phase-grown double layer (n−/n), showed a d.c. characteristic with a good saturation range and a switching response of 35 ps risetime.
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Development and technological realization of components Gallium Nitride (GaN) HEMTs with "Normally-Off" functionality "Normally-Off" functionality

open access: yes, 2021
Thanks to their high breakdown voltage and ultrahigh power density operation, AlGaN/GaN HEMTs stand out as promising candidates for next-generation of high-speed switching devices. While most of the demonstrated AlGaN/GaN HEMTs are inherently normally-on with a negative gate threshold voltage, normally-off mode is strongly demanded to fulfill the ...
openaire   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Evaluation de la robustesse d'une technologie HEMT GaN normally-off à implantation d’ions fluorures co-intégrée avec une technologie HEMT GaN normally-on [PDF]

open access: yes, 2021
Thanks to the outstanding properties of GaN, such as its wide band gap, its high critical electric field, its ability to operate at high temperatures and its high frequency performances, GaN-based HEMTs are considered as the best candidates for the next ...
Albany, Florent
core  

Activity-dependent disruption of intersublaminar spaces and ABAKAN expression does not impact functional on and off organization in the ferret retinogeniculate system

open access: yesNeural Development, 2011
In the adult visual system, functionally distinct retinal ganglion cells (RGCs) within each eye project to discrete targets in the brain. In the ferret, RGCs encoding light increments or decrements project to independent On and Off sublaminae within each
Sun Chao   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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