Results 61 to 70 of about 16,770 (217)

The Anti‐Inflammatory Effect of Normothermic Machine Perfused Human Kidneys on Monocyte‐Derived Dendritic Cells

Artificial Organs, EarlyView.
The immunogenicity of donor kidneys on NMP can be studied using monocyte‐derived dendritic cells. Incubation with perfusate showed an anti‐inflammatory dendritic cell phenotype and function that suggests the release of an anti‐inflammatory factor or factors during NMP. ABSTRACT Background The immunomodulatory activity of normothermic machine perfusion (
Laura W. D. Knijff, Asel S. Arykbaeva, Sandra W. van der Kooij, Dorottya K. de Vries, Mieke F. van Essen, Ian P. J. Alwayn, Henri G. D. Leuvenink, Rutger J. Ploeg, Cees van Kooten   +8 more
wiley   +1 more source

Normothermic regional perfusion – What is the benefit? [PDF]

Journal of Hepatology, 2019
Normothermic regional ...
Schlegel, Andrea, Muiesan, Paolo, Dutkowski, Philipp   +2 more
openaire   +3 more sources

Heart Donation After Controlled Circulatory Death in Noncardiac Surgery Hospitals With a Mobile Heart Team: A Case Series From an Italian Regional Program and Integrated Review of the Literature

Artificial Organs, EarlyView.
In this series of 19 DCD donors using TA‐NRP, 89.5% of hearts were successfully transplanted with no PGD, no postoperative ECMO, and no 30‐day mortality, demonstrating the feasibility and safety of this approach. ABSTRACT Controlled donation after circulatory death (cDCD) with thoracoabdominal normothermic regional perfusion (TA‐NRP) has emerged ...
Maria Benedetto, Valentina Roncarati, Arianna Campana, Erika Cordella, Domenico Nocera, Sofia Martin‐Suarez, Luca Botta, Davide Pacini, Letizia Perinati, Massimo Baiocchi, Tommaso Tonetti, Fabrizio Monaco   +11 more
wiley   +1 more source

Ex-Vivo Perfusion of Limb Vascularized Composite Allotransplants: A Systematic Review of Published Protocols

Transplant International
Vascularized composite allotransplantation (VCA) has revolutionized restorative surgery of devastating injuries. Unfortunately, these grafts undergo significant injury during prolonged cold ischemia and subsequent reperfusion.
Tessa E. Muss, Eleni M. Drivas, Amanda H. Loftin, Amanda H. Loftin, Yinan Guo, Yichuan Zhang, Christopher D. Lopez, Alisa O. Girard, Alisa O. Girard, Isabel V. Lake, Bashar Hassan, Bashar Hassan, Richa Kalsi, Byoung Chol Oh, Gerald Brandacher, Gerald Brandacher   +15 more
doaj   +1 more source

A fully automated normothermic machine perfusion system for kidney grafts supporting physiological motivated flow profiles

Current Directions in Biomedical Engineering, 2023
Research showed that the normothermic machine perfusion of kidneys can enable prolonged storage and improve conditions compared to traditional cold storage. For research in this area, there is a demand for a long-term in vitro perfusion setup.
Wiartalla Marc, Berg Frederik, Kühn Jahn, Buglowski Mateusz, Bleilevens Christian, Kowalewski Stefan, Stollenwerk André   +6 more
doaj   +1 more source

Death Determination, the Dying Process and the Dead Donor Rule: A Critical Analysis of the Italian 20‐Minute No‐Touch Period in Controlled Donation After Circulatory Determination of Death

Bioethics, EarlyView.
ABSTRACT In Italy, controlled Donation after Circulatory Determination of Death (cDCDD) requires a 20‐min no‐touch period documented by continuous electrocardiographic monitoring. Since Italian law adopts a single brain‐based definition of death, this procedure serves as an indirect determination of the irreversible cessation of all brain functions ...
Lucia Craxì
wiley   +1 more source

Superior hepatic mitochondrial oxidation-reduction state in normothermic cardiopulmonary bypass [PDF]

, 2001
Objective: This study is the first comparative investigation of hepatic blood flow and oxygen metabolism during normothermic and hypothermic cardiopulmonary bypass. Methods: Twenty-four patients undergoing coronary bypass operations were randomly divided
Hashimoto, Kazuhiro, Oshiumi, Motohiro, Hachiya, Takashi, Takakura, Hiromitsu, Onoguchi, Katsuhisa, Sasaki, Tatsuumi, Takeuchi, Shigeyuki   +6 more
core   +1 more source

Experimental perfusion device for preservation of donor’s liver

Вестник хирургии имени И.И. Грекова, 2017
OBJECTIVE. The authors aimed to develop complex perfusion medical device in order to successfully maintain viability of donor liver until transplantation. MATERIAL AND METHODS.
S. F. Bagnenko, O. N. Reznik, A. E. Skvortsov, A. V. Lopota, N. A. Gryaznov, V. V. Kharlamov, G. S. Kireeva   +6 more
doaj   +1 more source

Equine vegetative endocarditis and vertebral osteomyelitis due to refractory Erysipelothrix rhusiopathiae infection

Equine Veterinary Education, EarlyView.
Summary Erysipelothrix rhusiopathiae was the causative agent of vegetative endocarditis and vertebral osteomyelitis in a 24‐year‐old Irish draught gelding that presented with prolonged history of intermittent pyrexia and tachycardia. Clinical investigations revealed persistently reduced neck mobility, tachydysrhythmia and episodic pyrexia up to 41°C ...
E. Kolovou, Z. Daobry, Â. J. F. Mendes, G. Weller, S. Radhakrishnan, M. S. I. Sajib, M. Fuentes, F. Zendri, T. Forde, W. Weir, J. Del‐Pozo, D. G. M. Sutton   +11 more
wiley   +1 more source

Ex-vivo normothermic liver perfusion: an update.

, 2010
PURPOSE OF REVIEW: There is increasing disparity between the supply of acceptable donor organs and the number of potential transplant recipients. The shortage of organs for transplantation demands optimal utilization of a wider spectrum of donor organs ...
Friend, PJ, Vogel, T, Friend, Peter, Brockmann, JG   +3 more
core   +1 more source