Results 41 to 50 of about 16,770 (217)

Evaluation of Normothermic Flush and Perfusion Techniques, Using a Novel Normothermic Preservation Solution, in an Isolated Porcine Haemoperfusion Model

, 2010
The basis of the work in this thesis is an assessment of renal preservation techniques. The first chapter comprises a review of the pathophysiology of ischaemic injury and the role of hypothermic preservation.
Mark Kay (253438)
core   +7 more sources

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Epilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson, Lucie Suchomelova, Claude G. Wasterlain   +2 more
wiley   +1 more source

Normothermic Ex vivo Lung Perfusion: Toronto Protocol

, 2021
The advent of normothermic ex vivo lung perfusion (EVLP) has allowed for significant increases in lung transplant volume, allowing for the recovery of lungs deemed unsuitable for transplantation.
Marcelo Cypel (38994), Manyin Chen (11261220), Jonathan Yeung (5988512), Rafaela Ribeiro (3620537), Aizhou Wang (11261223), Shaf Keshavjee (131315), Hemant Gokhale (11261217)   +6 more
core   +1 more source

Extending heart preservation to 24 h with normothermic perfusion

Frontiers in Cardiovascular Medicine
Cold static storage (CSS) for up to 6 h is the gold standard in heart preservation. Although some hearts stored over 6 h have been transplanted, longer CSS times have increased posttransplant morbimortality.
Brianna L. Spencer, Spencer K. Wilhelm, Christopher Stephan, Kristopher A. Urrea, Daniela Pelaez Palacio, Robert H. Bartlett, Daniel H. Drake, Daniel H. Drake, Alvaro Rojas-Pena, Alvaro Rojas-Pena   +9 more
doaj   +1 more source

Warmed intravenous fluid administration attenuated a reduction in body temperature in anaesthetised horses

Equine Veterinary Journal, EarlyView.
Abstract Background Peri‐anaesthetic hypothermia is a well‐documented complication of general anaesthesia and is associated with prolonged recovery, impaired wound healing, and delayed coagulation. Fluid warmers can be used to mitigate heat loss, but there is little evidence supporting their effectiveness in equine anaesthesia.
Miranda P. Starr, Alycia Frampton, Allison Mika, Klaus Hopster, Hope Douglas   +4 more
wiley   +1 more source

The use of normothermic liver preservation in combined liver and lung transplantation: A single-center experience

, 2022
Combined liver and lung transplantation (CLLT) is indicated in patients with both end-stage liver and lung disease. Ex-situ normothermic machine perfusion (NMP) has been previously used for extended normothermic lung preservation in CLLT.
Shamaa, Omar, Crombez, Catherine, Konel, Jonathan M, Yoshida, Atsushi, Rizzari, Michael, Shamaa, Tayseer M, Nagai, Shunji, Abouljoud, Marwan S, Shimada, Shingo, Mohamed, Adhnan, Ivanics, Tommy, Collins, Kelly, Kitajima, Toshihiro   +12 more
core   +1 more source

Decreased cAMP Level and Decreased Downregulation of β1‐Adrenoceptor Expression in Therapeutic Hypothermia‐Resuscitated Myocardium Are Associated With Improved Post‐Resuscitation Myocardial Function

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundEpinephrine administered during cardiopulmonary resuscitation (CPR) is associated with severe post‐resuscitation myocardial dysfunction.
Wei Wang, Tianfeng Hua, Hao Li, Xiaobo Wu, Jennifer Bradley, Mary Ann Peberdy, Joseph P. Ornato, Wanchun Tang   +7 more
doaj   +1 more source

The Dead Donor Rule and Normothermic Regional Perfusion

Hastings Center Report, EarlyView.
Abstract Normothermic regional perfusion (NRP) can be used after the circulatory determination of death to prevent or minimize organ damage before the donor's organs are retrieved. It involves restarting circulation within the donor's body to reperfuse abdominal and thoracic organs while occluding the arteries that supply oxygenated blood to the brain ...
Andrew McGee, Brendan Parent, Dale Gardiner, Drew Carter   +3 more
wiley   +1 more source

Interleukin‐37 Enhances Liver NK Cell Cytotoxicity and Improves Recurrence‐Free Survival in Hepatocellular Carcinoma Patients

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Hepatocellular carcinoma (HCC) remains a major cause of cancer‐related mortality worldwide, and postoperative recurrence continues to limit long‐term survival. Liver‐resident natural killer (NK) cells are key effectors of antitumor immunity in the hepatic microenvironment. Interleukin‐37 (IL‐37), an anti‐inflammatory cytokine, has
Yuki Imaoka, Masahiro Ohira, Yuka Tanaka, Toshihiro Nakayama, Miho Akabane, Shinichiro Yokota, Sheri M. Krams, Olivia M. Martinez, Carlos O. Esquivel, Kazunari Sasaki, Hideki Ohdan   +10 more
wiley   +1 more source

Ex-vivo normothermic perfusion in renal transplantation: past, present and future [PDF]

, 2017
$\textbf{PURPOSE OF REVIEW}$: Marginal donor kidneys make up a substantial proportion of transplanted kidneys. Nonetheless, they are more susceptible to injury during procurement and preservation.

core   +2 more sources