Results 31 to 40 of about 566,967 (348)

A crack-like notch analogue for a safe-life fretting fatigue design methodology [PDF]

open access: yes, 2003
Various analogies have recently been proposed for comparing the stress fields induced in fretting fatigue contact situations, with those of a crack and a sharp or a rounded notch, resulting in a degree of uncertainty over which model is most appropriate ...
Ciavarella, M.
core   +1 more source

Knockdown of Butyrylcholinesterase but Not Inhibition by Chlorpyrifos Alters Early Differentiation Mechanisms in Human Neural Stem Cells

open access: yesToxics, 2018
Butyrylcholinesterase (BChE) is the evolutionary counterpart to acetylcholinesterase (AChE). Both are expressed early in nervous system development prior to cholinergic synapse formation.
Angela K. Tiethof   +2 more
doaj   +1 more source

Active control of vibrant actuators with adaptive adjustment of the reference [PDF]

open access: yes, 1999
An improved adaptive filter for eliminating periodic vibrations of unknown frequency in rotary machinery is presented. The proposed canceller is based on a usual bank of digital adaptive notch filters, each filter tuned in the cancellation of one ...
Bertran Albertí, Eduardo   +1 more
core   +1 more source

Resolving Astrocyte Heterogeneity in the CNS

open access: yesFrontiers in Cellular Neuroscience, 2017
Astrocytes play essential roles in nearly all aspects of brain function from modulating synapses and neurovasculature to preserving appropriate extracellular solute concentrations. To meet the complex needs of the central nervous system (CNS), astrocytes
W. Todd Farmer, Keith Murai
doaj   +1 more source

Notch signaling and Notch signaling modifiers [PDF]

open access: yesThe International Journal of Biochemistry & Cell Biology, 2011
Originally discovered nearly a century ago, the Notch signaling pathway is critical for virtually all developmental programs and modulates an astounding variety of pathogenic processes. The DSL (Delta, Serrate, LAG-2 family) proteins have long been considered canonical activators of the core Notch pathway. More recently, a wide and expanding network of
openaire   +2 more sources

Suppression of Second-Order Harmonic Current for Droop-Controlled Distributed Energy Resource Converters in DC Microgrids [PDF]

open access: yes, 2020
Droop-controlled distributed energy resource converters in dc microgrids usually show low output impedances. When coupled with ac systems, second-order harmonics typically appear on the dc-bus voltage, causing significant harmonic currents at the ...
Caldognetto, Tommaso   +3 more
core   +1 more source

Notch one for activating NOTCH [PDF]

open access: yesScience-Business eXchange, 2011
Vanderbilt researchers have identified downregulation of NOTCH signaling as a mechanism tumors use to evade the immune system, suggesting that restoring activation of the pathway could improve cancer immunotherapy. Researchers have been split on whether it is better to up- or downregulate NOTCH.
openaire   +1 more source

Cathepsin C-driven enhancement of neutrophil extracellular trap formation contributes to acute lung injury

open access: yesiScience
Summary: Acute lung injury (ALI) is a severe pulmonary inflammatory disease with high morbidity and mortality rates. The pulmonary inflammatory phenotype of ALI is driven by the excessive aggregation and activation of neutrophils, triggering a cytokine ...
Xinyu Wu   +13 more
doaj   +1 more source

Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling

open access: yeseLife, 2015
Angiopoietin-like proteins (angptls) are capable of ex vivo expansion of mouse and human hematopoietic stem and progenitor cells (HSPCs). Despite this intriguing ability, their mechanism is unknown.
Michelle I Lin   +18 more
doaj   +1 more source

PI3K and Notch signaling pathway play a synergistic regulatory role in the proliferation and activation of CD4+T cells in peripheral blood of patients with psoriasis vulgaris

open access: yesPifu-xingbing zhenliaoxue zazhi, 2022
Objective To study effects of phosphoinositide 3 kinase (PI3K) and Notch signaling pathway on the proliferation and activation of CD4+ T cells in peripheral blood of patients with psoriasis vulgaris.
Jia LIU, Ming WEI
doaj   +1 more source

Home - About - Disclaimer - Privacy