Results 81 to 90 of about 47,863 (285)

Modeling heterogeneity in large‐scale bioreactors using the method of moments with a truncated normal distribution

open access: yesAIChE Journal, EarlyView.
ABSTRACT Large‐scale bioreactors in industrial bioprocesses pose challenges due to extracellular concentration gradients and intracellular heterogeneity. This study introduces a novel approach integrating the method of moments with truncated normal distributions (MM‐TND) to model intracellular heterogeneity while maintaining computational feasibility ...
Ittisak Promma   +3 more
wiley   +1 more source

Physiological Profile of Neuropeptide Y-Expressing Neurons in Bed Nucleus of Stria Terminalis in Mice: State of High Excitability

open access: yesFrontiers in Cellular Neuroscience, 2018
Both, the anterior bed nucleus of the stria terminalis (BNST) and the neuropeptide Y (NPY) system are involved in shaping fear and defensive responses that adapt the organism to potentially life-threatening conditions.
Achim Leonhard Walter   +5 more
doaj   +1 more source

The Role of Neuropeptide Y in Adipocyte-Macrophage Crosstalk during High Fat Diet-Induced Adipose Inflammation and Liver Steatosis

open access: yesBiomedicines, 2021
Obesity is associated with an increased risk of non-alcoholic fatty liver disease (NAFLD), which is initiated by adipocyte-macrophage crosstalk. Among the possible molecules regulating this crosstalk, we focused on neuropeptide Y (NPY), which is known to
Seongjoon Park   +4 more
doaj   +1 more source

Cellpose+, a Morphological Analysis Tool for Feature Extraction of Stained Cell Images

open access: yesAdvanced Intelligent Discovery, EarlyView.
We introduce Cellpose plus, a morphological and geometrical analysis tool for feature extraction of stained cell images built over Cellpose, a state‐of‐the‐art cell segmentation framework. We also introduce a dataset of DAPI and FITC stained cells to which our new method is applied.
Israel A. Huaman   +10 more
wiley   +1 more source

Effect of Resistance Training on Appetite Regulation and Level of Related Peptidesin Sedentary Healthy Men

open access: yesMedical Laboratory Journal, 2017
Background and Objectives: Resistance training is a key component of exercise recommendations for weight control, yet very little is known about the effects of resistance training on appetite and related peptides.
A Jafari   +3 more
doaj  

Higher Serum Neuropeptide Y Levels Are Associated with Metabolically Unhealthy Obesity in Obese Chinese Adults: A Cross-Sectional Study

open access: yesMediators of Inflammation, 2020
Objective. Neuropeptide Y (NPY), an orexigenic peptide known to cause hyperphagia, has been involved in the occurrence and development of obesity. However, differences in the distribution of serum NPY levels in obese phenotypes (including metabolically ...
Hao-Neng Tang   +6 more
doaj   +1 more source

Pancreatic beta cells synthesize neuropeptide Y and can rapidly release peptide co-transmitters. [PDF]

open access: yesPLoS ONE, 2011
In addition to polypeptide hormones, pancreatic endocrine cells synthesize a variety of bioactive molecules including classical transmitters and neuropeptides. While these co-transmitters are thought to play a role in regulating hormone release little is
Matthew D Whim
doaj   +1 more source

Neuropeptide Y Variation Is Associated With Altered Static and Dynamic Functional Connectivity of the Salience Network

open access: yesFrontiers in Systems Neuroscience, 2021
Neuropeptide Y (NPY) is a neurotransmitter that has been implicated in the development of anxiety and mood disorders. Low levels of NPY have been associated with risk for these disorders, and high levels with resilience.
Katherine G. Warthen   +5 more
doaj   +1 more source

Targeted Proteomics upon Treatment with Tofersen Identifies Novel Response Markers for Superoxide Dismutase 1‐Linked Amyotrophic Lateral Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Tofersen is the first effective and approved therapy for superoxide dismutase 1 (SOD1)‐associated amyotrophic lateral sclerosis (ALS [SOD1‐ALS]). Following treatment with tofersen, neurofilament levels in patients' cerebrospinal fluid (CSF) and serum seem to respond earlier than clinical parameters.
Christina Steffke   +36 more
wiley   +1 more source

Galanin decreases NPYY1R internalization and β- Arrestin2 recruitment [PDF]

open access: yes, 2015
We have recently described a Galanin receptor 2(GALR2) and Neuropeptide Y Y1 receptor(NPYY1R) interaction at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers.
Borroto-Escuela, Dasiel   +8 more
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