Results 111 to 120 of about 2,154 (127)

Integrated Omics Approach to Delineate the Mechanisms of Doxorubicin-Induced Cardiotoxicity. [PDF]

Pharmaceuticals (Basel)
Dabour MS, Abdelgawad IY, Sadaf B, Daniel MR, Grant MKO, Blaes AH, Jacobson PA, Zordoky BN.   +7 more
europepmc   +1 more source

Influence of lighting on sleep behaviour, circadian rhythm and spontaneous blink rate in stabled riding school horses (Equus caballus). [PDF]

PLoS One
Greening L, Harkin E, Kyriazopoulou P, Heppelthwaite Z, Aragona F, Browne JA, Hemmings A, Williams JM, Murphy BA.   +8 more
europepmc   +1 more source

Novel CLOCK and NR1D2 variants in 64 sighted Japanese individuals with non-24-hour sleep-wake rhythm disorder

Novel CLOCK and NR1D2 variants in 64 sighted Japanese individuals with non-24-hour sleep-wake rhythm disorder
openaire   +1 more source

Co-regulation of Nr1d1 and Pparα in age-related changes of lipid metabolism and its modulation by calorie restriction. [PDF]

Aging (Albany NY)
Noh SG, Kim HW, Kim S, Yu BP, Yoon JH, Chung KW, Lee J, Chung HY.   +7 more
europepmc   +1 more source

Hepatic vagal afferents convey clock-dependent signals to regulate circadian food intake. [PDF]

Science
Woodie LN, Melink LC, Midha M, de Araújo AM, Geisler CE, Alberto AJ, Krusen BM, Zundell DM, de Lartigue G, Hayes MR, Lazar MA.   +10 more
europepmc   +1 more source

A robust negative association between estimated tumour circadian clock function and survival in early stage breast cancer

Vasilyev V, Vlachou D, Giacchetti S, Bjarnason GA, Martino TA, Levi F, Dallmann R, Rand DA.   +7 more
europepmc   +1 more source

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Circadian regulator NR1D2 regulates glioblastoma cell proliferation and motility

Oncogene, 2018
Nuclear receptor NR1D2 is originally characterized as the repressor of genes involved in circadian rhythm. Recently, it is documented that NR1D2 is overexpressed in various cancers. However, the pathways and biological functions that NR1D2 involved in cancers remain poorly understood. Here, we reported that NR1D2 was abundant in human glioblastoma (GBM)
, Qianqian Wang
exaly   +3 more sources

Downregulation of the core circadian gene Nr1d2 in the lacrimal gland contributes to postoperative dry eye disease by impairing lipid metabolism

Ocular Surface
Dry eye disease (DED) is a prevalent complication after refractive surgery, and its underlying mechanisms are not fully understood. Given that circadian rhythm tightly regulates tear secretion, this study aims to investigate the circadian changes in the lacrimal gland after corneal refractive surgery and the associated mechanisms.C57/BL6 mice underwent
Keming Yu
exaly   +3 more sources

Mesenchymal Stem Cells Alleviate Mouse Sepsis-Induced Cardiomyopathy by Inhibiting the NR1D2/LCN2 Pathway

Journal of Cardiovascular Pharmacology
Abstract: Sepsis is characterized as a systemic inflammatory response syndrome resulting from infection, leading to the development of multiple organ dysfunction syndrome. Sepsis-induced cardiomyopathy (SICM) is a frequently encountered condition in clinical settings.
Cheng Jiang
exaly   +3 more sources

NR1D2 Knockdown Alleviates Myocardial Infarction through Nrf2 Signaling Pathway Activation

Cardiovascular Drugs and Therapy
Ting Wang, Helong Xiao, Meijian Yang, Jing Liu, Yang Yang   +4 more
exaly   +2 more sources