Results 61 to 70 of about 3,079 (182)
Clinical Genetics, EarlyView.Opticus atrophy—Genetic testing with WES/WGS in 62 patients with optic atrophy provided a genetic diagnosis in 21 patients (33.9%). 42.9% of these involved non‐OPA1 genes, including WFS1, ACO2, NR2F1, UCHL1, CACNA1F, and COQ2, where the genetic diagnosis prompted additional clinical evaluation, surveillance, or therapeutic intervention.
Katrine M. Johannesen +9 more
wiley +1 more source
Understanding exosomes in diabetic wound healing
Periodontology 2000, EarlyView.Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad +4 more
wiley +1 more source
Additional file 3: of NR2F1 stratifies dormant disseminated tumor cells in breast cancer patients
, 2018 Figure S2. Illustration of the classification system for NR2F1 expression of DTC prospectively chosen for the present study. NR2F1low DTC (A–C). (A) Cluster of three DTCs identified by AE1AE3 in red fluorescence and a morphology compatible with tumor ...
Anne Renolen (5857319) +8 more
core +1 more source
NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes [PDF]
Nature Communications, 2015 Metastases can originate from disseminated tumour cells (DTCs), which may be dormant for years before reactivation. Here we find that the orphan nuclear receptor NR2F1 is epigenetically upregulated in experimental head and neck squamous cell carcinoma (HNSCC) dormancy models and in DTCs from prostate cancer patients carrying dormant disease for 7-18 ...
Sosa, Maria Soledad +14 more
openaire +2 more sources
New Insights into the Diverse Functions of the NR2F Nuclear Orphan Receptor Family
Frontiers in Bioscience-Landmark, 2023 Following gene expansion during evolution, today’s phylogenetic tree of the NR2F family of nuclear orphan receptors in mammals is represented by three different isoforms: NR2F1, NR2F2, and NR2F6.
Tajana Sajinovic, Gottfried Baier
doaj +1 more source
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.Sex‐stratified analyses of the TCGA and CGGA cohorts have identified promoter‐proximal TACSTD2 CpG sites where methylation shows opposite survival associations in males and females, is independent of copy number, and correlates with TACSTD2 expression.
Tahreem Fatima
wiley +1 more source
Supplementary Figure from NR2F1 Is a Barrier to Dissemination of Early-Stage Breast Cancer Cells
, 2022 Supplementary Figure from NR2F1 Is a Barrier to Dissemination of Early-Stage Breast Cancer ...
Nupura Kale (14954382) +11 more
core +1 more source
European Journal of HistochemistryAdult neurogenesis in mice occurs in specialized brain niches, including the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone (SGZ) of the dentate gyrus, where neural stem cells (NSCs) balance quiescence and activation towards
GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
doaj +1 more source
iMetaMed, Volume 2, Issue 2, June 2026.Clinical phases and classification of breast tumor dormancy. Tumor dormancy is described as the period after treatment until residual tumor cells become detectable as relapsing disease in clinic. During the period of clinical tumor dormancy, tumor mass dormancy and cellular dormancy may coexist.
Shu Chen +4 more
wiley +1 more source
, 2013 A) Heatmap of expression correlation clustering analysis of 412 genes (which have 1-1-1 mouse-rat-human orthologues) that are differentially expressed between mammary gland samples from megadeletion (MD) and wild type mice (WT), both FVB.
Jill D. Haag (220668) +17 more
core +1 more source