Results 81 to 90 of about 3,079 (182)
, 2021 The neocortex, the most recently evolved brain region in mammals, is characterized by its unique areal and laminar organization. Distinct cortical layers and areas can be identified by the presence of graded expression of transcription factors and ...
Regondi M. C. +12 more
core +1 more source
Abstract 3922: NR2F1 limits dissemination and stemness of early breast cancer cells
, 2017 Tumor cells derived from MMTV-Neu mouse models or human ErBb2+ primary tumors are known to be able to complete all steps of the metastatic cascade. However, new evidence show that Neu+ early cancer cells derived from early stages of tumor progression ...
Maria Soledad Sosa
core +1 more source
Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery
MedComm – Oncology, Volume 5, Issue 1, March 2026.This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem +9 more
wiley +1 more source
Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima +9 more
wiley +1 more source
Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming
Advanced Science, Volume 13, Issue 6, 30 January 2026.Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu +13 more
wiley +1 more source
Additional file 2: of NR2F1 stratifies dormant disseminated tumor cells in breast cancer patients
, 2018 Figure S1. AE1AE3/NR2F1 DIF staining on normal MNCs spiked with breast cancer cell line cells. The first row shows normal MNCs (AE1AE2-negative) and one breast cancer cell line cell (MCF7; AE1AE3-positive).
Anne Renolen (5857319) +8 more
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Advanced Science, Volume 13, Issue 5, 27 January 2026.This study shows that ERK/PKA upregulation in mammalian cortical radial glia (RGs) sustains neurogenesis and suppresses gliogenesis. YAP/TAZ activation promotes ependymal cell formation, while enhanced SHH‐SMO signaling induces astrocyte, oligodendrocytes, and olfactory bulb interneuron generation.
Zhuangzhi Zhang +13 more
wiley +1 more source
Andrology, Volume 14, Issue 1, Page 210-227, January 2026.Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody +6 more
wiley +1 more source
LncRNA NR2F1-AS1 promotes proliferation and metastasis of ESCC cells via regulating EMT.
European review for medical and pharmacological sciences, 2020 The aim of this study was to explore the expression of long non-coding ribonucleic acid (lncRNA) nuclear receptor subfamily 2 group F member 1-antisense RNA 1 (NR2F1-AS1) in esophageal squamous cell carcinoma (ESCC) tissues and cells and to investigate its effects on ESCC proliferation and metastasis.The expression level of NR2F1-AS1 in 51 pairs of ...
Ren, P. +4 more
openaire +2 more sources
European Journal of HistochemistryNeural stem cells (NSCs) in the adult mammalian brain generate new neurons supporting critical sensory and cognitive functions. In rodents, these NSCs are located in the subventricular zone (SVZ) and the subgranular zone (SGZ) of the hippocampus.
GEI - SOCIETÀ ITALIANA DI BIOLOGIA DELLO SVILUPPO E DELLA CELLULA
doaj +1 more source