Results 231 to 240 of about 225,391 (343)

Iron-Based Nanoplatforms Achieve Hepatocellular Carcinoma Regression Through a Cascade of Effects

International Journal of Nanomedicine
Kunzhao Huang,* Xiaoyuan Yi,* Huaying Xie, Jianzhang Luo, Qingyu Zeng, Feifei He, Liyan Wang Digestive Department, The Affiliated Hospital of Guilin Medical College, Guilin, 541001, People’s Republic of China*These authors contributed equally
Huang K, Yi X, Xie H, Luo J, Zeng Q, He F, Wang L   +6 more
doaj  

Erythropoietin preserves outer blood-retinal barrier integrity in diabetic retinopathy via AMPK-dependent autophagy and Nrf2 signaling. [PDF]

J Cereb Blood Flow Metab
Jang HY, Jiang H, Park JJ, Wu J, Jiang W, Kim JH.   +5 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Effective-Component Compatibility of Bufei Yishen Formula III Suppresses Mitochondrial Oxidative Damage in COPD: Via Pkm2/Nrf2 Pathway

International Journal of COPD
Yang Liu,1 Lanxi Zhang,2 Jie Zhao,1,3 Ruilong Lu,1 Xuejie Shao,1 Kexin Xu,1 Jiansheng Li,1,3,4,* Yange Tian1,3,* 1Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-Constructed by Henan Province and Education ...
Liu Y, Zhang L, Zhao J, Lu R, Shao X, Xu K, Li J, Tian Y   +7 more
doaj  

The Diet-Multiple Sclerosis Connection: Oxidative Stress and Emerging Mechanisms. [PDF]

Mol Neurobiol
Bucciero C, Croce A, Castellano G, Beguinot F, Formisano P, Portella G, Ulianich L, Fiory F, Malfitano AM.   +8 more
europepmc   +1 more source

Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

Hepatology, 2016
Xiaofang Sun, Z. Ou, Ruochan Chen, X. Niu, De Chen, R. Kang, D. Tang   +6 more
semanticscholar   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Polystyrene Nanoplastics induced placental toxicology by activating Keap1-mediated ferroptosis via METTL3-dependent m6A methylation. [PDF]

Cell Biol Toxicol
Chen Y, Liu Y, Zhang M, Li S, Yan Y, Yin C.   +5 more
europepmc   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

GSK3β promotes p53/Nrf2-dependent expression of the stress response protein REDD2 in retinal Müller glia exposed to hyperlipidemic conditions. [PDF]

Exp Eye Res
VanCleave AM, Sunilkumar S, Toro AL, Kimball SR, Dennis MD.   +4 more
europepmc   +1 more source