Results 121 to 130 of about 15,068 (213)

Global sensitivity analysis–NRP1 following perturbations.

This panel shows how changing the various trafficking and production parameters impacts the simulation predictions to be compared two key experimental data points: the change in whole cell NRP1 two hours after CHX administration (A) and the change in ...
Kaitlyn M. Quigley (17921748), Anita Kovacs-Kasa (17921751), Brian H. Annex (7878503), Karina Kinghorn (5291528), Victoria L. Bautch (17921754), Feilim Mac Gabhann (65849), Sarvenaz Sarabipour (379994)   +6 more
core   +1 more source

NRP1 interacts with endoglin and VEGFR2 to modulate VEGF signaling and endothelial cell sprouting

Communications Biology
Endothelial cells express neuropilin 1 (NRP1), endoglin (ENG) and vascular endothelial growth factor receptor 2 (VEGFR2), which regulate VEGF-A-mediated vascular development and angiogenesis.
Swati Sharma, Marcelo Ehrlich, Manqi Zhang, Gerard C. Blobe, Yoav I. Henis   +4 more
doaj   +1 more source

Global sensitivity analysis–NRP1 on the surface.

This panel shows how changing the various trafficking and production parameters impacts the simulation predictions to be compared two key experimental data points: the absolute number of surface NRP1 (B) and the percentage of cell NRP1 that is on the ...
Kaitlyn M. Quigley (17921748), Anita Kovacs-Kasa (17921751), Brian H. Annex (7878503), Karina Kinghorn (5291528), Victoria L. Bautch (17921754), Feilim Mac Gabhann (65849), Sarvenaz Sarabipour (379994)   +6 more
core   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

NRP1 Gene [PDF]

, 2020
openaire   +1 more source

NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

, 2014
SummaryNeuropilin 1 (NRP1) modulates angiogenesis by binding vascular endothelial growth factor (VEGF) and its receptor, VEGFR2. We examined the consequences when VEGFR2 and NRP1 were expressed on the same cell (cis) or on different cells (trans). In cis,
Claesson-Welsh, Lena,, Koch, Sina, Adler, Jeremy,, Morin, Eric, Weström, Simone, Testini, Chiara, Le Jan, Sebastien,, Morin, Eric,, van Meeteren, Laurens A., Berger, Philipp, Björkelund, Hanna, Weström, Simone,, Adler, Jeremy, van Meeteren, Laurens A.,, Testini, Chiara,, Le Jan, Sébastien, Claesson-Welsh, Lena, Koch, Sina,   +17 more
core   +1 more source

Neuropilin 1 (NRP1) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Radiation-induced YAP/TEAD4 binding confers non-small cell lung cancer radioresistance via promoting NRP1 transcription

Cell Death and Disease
Despite the importance of radiation therapy as a non-surgical treatment for non-small cell lung cancer (NSCLC), radiation resistance has always been a concern, due to poor patient response and prognosis.
Mingwei Wang, Junxuan Yi, Hui Gao, Xinfeng Wei, Weiqiang Xu, Mingqi Zhao, Mengdie Zhao, Yannan Shen, Zhicheng Wang, Ning Wu, Wei Wei, Shunzi Jin   +11 more
doaj   +1 more source

Neuropilin 1 (NRP1) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Targeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis

Nature Communications
Neuropilin-1 (NRP1), a co-receptor for various cytokines, including TGF-β, has been identified as a potential therapeutic target for fibrosis. However, its role and mechanism in renal fibrosis remains elusive.
Yinzheng Li, Zheng Wang, Huzi Xu, Yu Hong, Mengxia Shi, Bin Hu, Xiuru Wang, Shulin Ma, Meng Wang, Chujin Cao, Han Zhu, Danni Hu, Chang Xu, Yanping Lin, Gang Xu, Ying Yao, Rui Zeng   +16 more
doaj   +1 more source