Transcription regulation of Nrp1 during endothelial cell differentiation
Various diseases, including cancer, stroke and heart attack, are associated with disruption of the vascular system. However, lack of a profound understanding of the transcription regulation during vascular development hinders the formation of effective molecular intervention strategies targeting angiogenesis. Here we describe an enhancer of Neuropilin1
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Dynamics of VEGF-A binding at VEGFR2 and NRP1 [PDF]
Vascular Endothelial Growth Factor A (VEGF-A) is a key mediator of angiogenesis, a process dysregulated in tumour development. Alternative splicing of the Vegfa gene leads to distinct endogenous VEGF-A isoforms with differential signalling and expression.
Peach, Chloe J
core
Transplacental transmission of SARS-CoV-2 infection via NRP1
El-Arabey, Amr Ahmed, Abdalla, Mohnad
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Enhancing Immunotherapeutic Response in Colorectal Cancer with a Neuropilin 1-Targeting Tumor-Penetrating Peptide. [PDF]
Fukugaki A +11 more
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[<i>Wenyang Huazhuo Tongluo</i> Formula promotes angiogenesis in systemic sclerosis dermal microvascular endothelial cells by regulating the Sema3A/Nrp1 pathway]. [PDF]
Guo K +7 more
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GLP-1 receptor agonists alleviate inflammatory responses and endothelial dysfunction in atherosclerosis by activating the Sema3A/NRP1 pathway. [PDF]
Hu L +5 more
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Neuropilin 1 (NRP1) conveys SEMA3A signals to restrict physiological angiogenesis. [PDF]
Spreafico M +12 more
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ALDH1A3 promotes the lung metastatic organotropism of pancreatic ductal adenocarcinoma through semaphorin signaling. [PDF]
Shen S +15 more
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