Results 31 to 40 of about 1,212,320 (287)

Environmental ciprofloxacin triggers pregnancy loss: senescence-driven miscarriage via TRIM21-mediated MFF degradationResearch in context

open access: yesEBioMedicine
Summary: Background: Antibiotic abuse has become a top public health problem worldwide. Ciprofloxacin (CIP) has the highest detection rate in human but its association with unexplained miscarriage (UM) is completely unknown.
Yi Sun (孙义)   +14 more
doaj   +1 more source

Some Results on Critical (P5, H)-free Graphs [PDF]

open access: yes
sponsorship: The research of Jan Goedgebeur is supported by Internal Funds of KU Leuven and a grant of the Research Foundation Flanders (FWO) with grant number G0AGX24N.
Huang, Shenwei   +3 more
core   +1 more source

Axon regeneration impediment: the role of paired immunoglobulin-like receptor B

open access: yesNeural Regeneration Research, 2015
Regenerative capacity is weak after central nervous system injury because of the absence of an enhancing microenvironment and presence of an inhibitory microenvironment for neuronal and axonal repair.
Jing Liu, Yan Wang, Wei Fu
doaj   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

open access: yesFEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li   +7 more
wiley   +1 more source

The role of the Rho/ROCK signaling pathway in inhibiting axonal regeneration in the central nervous system

open access: yesNeural Regeneration Research, 2015
The Rho/Rho-associated coiled-coil containing protein kinase (Rho/ROCK) pathway is a major signaling pathway in the central nervous system, transducing inhibitory signals to block regeneration.
Jing Liu, Hong-yan Gao, Xiao-feng Wang
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Microencapsulation improves inhibitory effects of transplanted olfactory ensheathing cells on pain after sciatic nerve injury

open access: yesNeural Regeneration Research, 2015
Olfactory bulb tissue transplantation inhibits P2X2/3 receptor-mediated neuropathic pain. However, the olfactory bulb has a complex cellular composition, and the mechanism underlying the action of purified transplanted olfactory ensheathing cells (OECs ...
Hao Zhao   +9 more
doaj   +1 more source

Integral representations of harmonic functions in half spaces☆☆The project supported by NSFC (Grant No.10371011) and by SRF for ROCS.SEM.

open access: yesBulletin des Sciences Mathématiques, 2007
AbstractIn this paper, using a modified Poisson kernel in an upper half-space, we prove that a harmonic function u(z) in a upper half space with its positive part u+(x)=max{u(x),0} satisfying a slowly growing condition can be represented by its integral in the boundary of the upper half space, the integral representation is unique up to the addition of
openaire   +1 more source

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang   +23 more
wiley   +1 more source

Comprehensive systematic review and meta-analysis of risk factors for childhood obesity in China and future intervention strategiesResearch in context

open access: yesThe Lancet Regional Health. Western Pacific
Summary: Background: Childhood obesity is a critical public health concern in China. This study identified the key determinants of childhood obesity in China and provided recommendations for future intervention strategies.
Yanfen Jiang   +12 more
doaj   +1 more source

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