Results 71 to 80 of about 64,272 (317)
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang+5 more
wiley +1 more source
The dominance of big teams in China's scientific output [PDF]
Modern science is dominated by scientific productions from teams. A recent finding shows that teams with both large and small sizes are essential in research, prompting us to analyze the extent to which a country's scientific work is carried out by big/small teams.
arxiv
Abstract For systems with unknown input disturbances, a robust state-space observer is designed to simultaneously estimate the system state, the finitely times derivatives of the fault, and the fault signal at the same time. The considered fault signal can be allowed to be unbounded provided its finitely times derivative is bounded.
Steven X. Ding, Zhiwei Gao, Y. Ma
openaire +2 more sources
Although several surgical procedures exist for treating cubital tunnel syndrome, the best surgical option remains controversial. To evaluate the efficacy of anterior subcutaneous transposition of the ulnar nerve in patients with moderate to severe ...
Wei Huang+5 more
doaj +1 more source
A fracture mechanics-based method for prediction of cracking of circular and elliptical concrete rings under restrained shrinkage [PDF]
A new experimental method, utilizing elliptical ring specimens, is developed for assessing the likelihood of cracking and cracking age of concrete subject to restrained shrinkage.
Dong, W, Wu, Z, Zhou, X
core +2 more sources
A review for grant application and merit review in the field of synthetic chemistry of NSFC from 2018 to 2020 [PDF]
Xuefeng Fu+4 more
openaire +1 more source
AbstractThis paper concerns the large time behavior of strong and classical solutions to the two-dimensional Stokes approximation equations for the compressible flows. We consider the unique global strong solution or classical solution to the two-dimensional Stokes approximation equations for the compressible flows with large external potential force ...
Feimin Huang+3 more
openaire +2 more sources
Ischemic preconditioning protects against ischemic brain injury
In this study, we hypothesized that an increase in integrin αv ß 3 and its co-activator vascular endothelial growth factor play important neuroprotective roles in ischemic injury. We performed ischemic preconditioning with bilateral common carotid artery
Xiao-meng Ma+5 more
doaj +1 more source
ABSTRACT Background and Objectives Ofatumumab, a fully human anti‐CD20 monoclonal antibody, is effective in reducing relapses and disability progression in patients with multiple sclerosis. This study aimed to examine immune profile changes associated with ofatumumab in a prospective cohort of Chinese patients with relapsing–remitting multiple ...
Shu Yang+9 more
wiley +1 more source
Protein-RNA interactions play critical roles in numerous biological processes such as posttranscriptional regulation and protein synthesis. However, experimental screening of protein-RNA interactions is usually laborious and time-consuming. It is therefore desirable to develop efficient bioinformatics methods to predict protein-RNA interactions, which ...
Zhi-Ping Liu, Hongyu Miao
openaire +3 more sources