Results 71 to 80 of about 64,272 (317)

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

open access: yesFEBS Open Bio, EarlyView.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang   +5 more
wiley   +1 more source

The dominance of big teams in China's scientific output [PDF]

open access: yesarXiv, 2020
Modern science is dominated by scientific productions from teams. A recent finding shows that teams with both large and small sizes are essential in research, prompting us to analyze the extent to which a country's scientific work is carried out by big/small teams.
arxiv  

Robust Fault Estimation for Vehicle Lateral Dynamic Systems11Partially supported by the NSFC Grant (60574026) and the Alexander von Humboldt Foundation (1117303)

open access: yesIFAC Proceedings Volumes, 2006
Abstract For systems with unknown input disturbances, a robust state-space observer is designed to simultaneously estimate the system state, the finitely times derivatives of the fault, and the fault signal at the same time. The considered fault signal can be allowed to be unbounded provided its finitely times derivative is bounded.
Steven X. Ding, Zhiwei Gao, Y. Ma
openaire   +2 more sources

Anterior subcutaneous transposition of the ulnar nerve improves neurological function in patients with cubital tunnel syndrome

open access: yesNeural Regeneration Research, 2015
Although several surgical procedures exist for treating cubital tunnel syndrome, the best surgical option remains controversial. To evaluate the efficacy of anterior subcutaneous transposition of the ulnar nerve in patients with moderate to severe ...
Wei Huang   +5 more
doaj   +1 more source

A fracture mechanics-based method for prediction of cracking of circular and elliptical concrete rings under restrained shrinkage [PDF]

open access: yes, 2014
A new experimental method, utilizing elliptical ring specimens, is developed for assessing the likelihood of cracking and cracking age of concrete subject to restrained shrinkage.
Dong, W, Wu, Z, Zhou, X
core   +2 more sources

A review for grant application and merit review in the field of synthetic chemistry of NSFC from 2018 to 2020 [PDF]

open access: yesSCIENTIA SINICA Chimica, 2021
Xuefeng Fu   +4 more
openaire   +1 more source

Convergence to equilibria and blowup behavior of global strong solutions to the Stokes approximation equations for two-dimensional compressible flows with large data☆☆Partially supported by the National Natural Science Foundation of China under contracts 10471138, 10601059, and 10526039 (Tianyuan Jijin); NSFC–NSAF Grant No. 10676037; 973 project of China, Grant No. 2006CB805902; Zheng Ge Ru Funds, Grants from RGC of HKSAR CUHK4028/04P and CUHK4299/02P.

open access: yesJournal de Mathématiques Pures et Appliquées, 2006
AbstractThis paper concerns the large time behavior of strong and classical solutions to the two-dimensional Stokes approximation equations for the compressible flows. We consider the unique global strong solution or classical solution to the two-dimensional Stokes approximation equations for the compressible flows with large external potential force ...
Feimin Huang   +3 more
openaire   +2 more sources

Ischemic preconditioning protects against ischemic brain injury

open access: yesNeural Regeneration Research, 2016
In this study, we hypothesized that an increase in integrin αv ß 3 and its co-activator vascular endothelial growth factor play important neuroprotective roles in ischemic injury. We performed ischemic preconditioning with bilateral common carotid artery
Xiao-meng Ma   +5 more
doaj   +1 more source

Reconstitution of CXCR3+ CCR6+ Th17.1‐Like T Cells in Response to Ofatumumab Therapy in Patients With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Ofatumumab, a fully human anti‐CD20 monoclonal antibody, is effective in reducing relapses and disability progression in patients with multiple sclerosis. This study aimed to examine immune profile changes associated with ofatumumab in a prospective cohort of Chinese patients with relapsing–remitting multiple ...
Shu Yang   +9 more
wiley   +1 more source

Prediction of Protein-RNA Interactions Using Sequence and Structure Descriptors**This work was partially supported by the National Natural Science Foundation of China (NSFC) Grant No. 31100949, the Scientific Research Foundation for the Returned Overseas Chinese Scholars, Ministry of Education of China, the Fundamental Research Funds of Shandong University Grant No. 2014TB006, University of Rochester Center for AIDS Research Grant P30 AI078498 (NIH/NIAID) and NIH R01 Grant GM100788-01.

open access: yesIFAC-PapersOnLine, 2015
Protein-RNA interactions play critical roles in numerous biological processes such as posttranscriptional regulation and protein synthesis. However, experimental screening of protein-RNA interactions is usually laborious and time-consuming. It is therefore desirable to develop efficient bioinformatics methods to predict protein-RNA interactions, which ...
Zhi-Ping Liu, Hongyu Miao
openaire   +3 more sources

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