Results 41 to 50 of about 769,634 (286)

Correction: Metformin limits osteoarthritis development and progression through activation of AMPK signalling

open access: yesAnnals of the Rheumatic Diseases, 2020
This work was supported by the National Institutes of Health (NIH) Grant R01AR070222 to DC. This work was also partially supported by grants from the National Nature Science Foundation of China (NSFC) (81620108018, 81930070), and Tianjin key research and
J. Li, Zhang
semanticscholar   +1 more source

Electrical stimulation does not enhance nerve regeneration if delayed after sciatic nerve injury: the role of fibrosis

open access: yesNeural Regeneration Research, 2015
Electrical stimulation has been shown to accelerate and enhance nerve regeneration in sensory and motor neurons after injury, but there is little evidence that focuses on the varying degrees of fibrosis in the delayed repair of peripheral nerve tissue ...
Na Han   +6 more
doaj   +1 more source

The current state and future prospects of the fundamental research on pediatric otorhinolaryngology: an analysis of application and funding data of the National Natural Science Foundation of China from 2009 to 2019

open access: yesAnnals of Translational Medicine, 2020
Background This study aimed to summarize the current situation and deficiencies of the fundamental research on pediatric otolaryngology-head and neck science.
Yihong Liu, Xiaobin Zhang
semanticscholar   +1 more source

A cascade model of information processing and encoding for retinal prosthesis

open access: yesNeural Regeneration Research, 2016
Retinal prosthesis offers a potential treatment for individuals suffering from photoreceptor degeneration diseases. Establishing biological retinal models and simulating how the biological retina convert incoming light signal into spike trains that can ...
Zhi-jun Pei   +4 more
doaj   +1 more source

Kalman Filtering for Discrete Stochastic Systems with Multiplicative Noises and Random Two-Step Sensor Delays

open access: yes, 2015
This work was supported in part by the National Natural Science Foundation of China (NSFC) under Grants 11271103 and 11301118.
Dongyan Chen   +3 more
semanticscholar   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li   +10 more
wiley   +1 more source

Biodegradable chitin conduit tubulation combined with bone marrow mesenchymal stem cell transplantation for treatment of spinal cord injury by reducing glial scar and cavity formation

open access: yesNeural Regeneration Research, 2015
We examined the restorative effect of modified biodegradable chitin conduits in combination with bone marrow mesenchymal stem cell transplantation after right spinal cord hemisection injury.
Feng Xue   +6 more
doaj   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Expression pattern of neuregulin-1 type III during the development of the peripheral nervous system

open access: yesNeural Regeneration Research, 2015
Neuregulin-1 type III is a key regulator in Schwann cell proliferation, committing to a myelinating fate and regulating myelin sheath thickness.
Liang-liang Huang   +3 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

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