Results 161 to 170 of about 1,883 (170)

Pharmacokinetic evaluation of neutral-sphinghomyelinase2 (nSMase2) inhibitor prodrugs in dogs

Drug Metabolism and Pharmacokinetics
Arina Ranjit, Lukas Tenora, Jesse Alt, Barbara Slusher, Rana Rais   +4 more
openaire   +1 more source

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Frontiers in Molecular Neuroscience, 2019
Martin Hallbeck, Christopher Sackmann, Valerie Sackmann   +2 more
exaly  

Regulation of Neutral Sphingomyelinase-2 (nSMase2) by Tumor Necrosis Factor-α Involves Protein Kinase C-δ in Lung Epithelial Cells

Molecular Pharmacology, 2008
Christopher J Clarke, Yusuf A. Hannun
exaly  

Role for Neutral Sphingomyelinase-2 in Tumor Necrosis Factor α-Stimulated Expression of Vascular Cell Adhesion Molecule-1 (VCAM) and Intercellular Adhesion Molecule-1 (ICAM) in Lung Epithelial Cellsp38 MAPK IS AN UPSTREAM REGULATOR OF nSMase2*

Journal of Biological Chemistry, 2007
Christopher J Clarke, Yusuf A. Hannun
exaly  

Myocardial reparative functions of exosomes from mesenchymal stem cells are enhanced by hypoxia treatment of the cells via transferring microRNA-210 in an nSMase2-dependent way

Artificial Cells, Nanomedicine and Biotechnology
Hong Yu, Jian Shen, Jian'an Wang
exaly  

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Frontiers in Immunology
Fabian Schumacher, Burkhard Kleuser, Marco van Ham   +2 more
exaly  

Small molecule inhibitors of neutral sphingomyelinase 2 (nSMase2) for the treatment of neurodegenerative diseases

2022
SLUSHER BARBARA, ROJAS CAMILO, THOMAS AJIT G, NENCKA RADIM, SALA MICHAL, HREBABECKY HUBERT, HAUGHEY NORMAN   +6 more
openaire   +1 more source

SMALL MOLECULE INHIBITORS OF NEUTRAL SPHINGOMYELINASE 2 (NSMASE2) FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES

2018
SLUSHER BARBARA, ROJAS CAMILO, THOMAS AJIT G, NENCKA RADIM, SÁLA MICHAL, HREBABECKY HUBERT   +5 more
openaire   +3 more sources

Involvement of Heat Shock Protein HSP70 and Ceramide Generator nSmase2 in IL-33 Driven Airway Disease

A108. COPD PATHOGENESIS: OPENING THE PANDORA BOX
O. Osorio, G.F. Hassan, H. Raphael, L. Cohen, D. Steinberg, C. Kluender, D.E. Byers, J. Alexander-Brett   +7 more
openaire   +1 more source

Novel Pyrazolo[1,5-a]pyrimidine-3,5-diamines as nSMase2 Inhibitors

ACS Medicinal Chemistry Letters
Steven H. Liang, Jian Rong
exaly