Results 91 to 100 of about 38,894 (153)

Additional file 1 of Development of novel monoclonal antibodies against nsp12 of SARS-CoV-2

Additional file1. Figure S1: Screening of anti-nsp12 mouse monoclonal antibodies using the culture supernatant of hybridomas. Figure S2: Selection of anti-nsp12 mouse monoclonal antibodies to discriminate between nsp12 of SARS-CoV and SARS-CoV-2.
Machitani, Mitsuhiro, Takei, Junko, Kaneko, Mika K., Ueki, Saori, Ohashi, Hirofumi, Watashi, Koichi, Kato, Yukinari, Masutomi, Kenkichi   +7 more
openaire   +1 more source

<b>Broadly cross-reactive mRNA COVID-19 vaccine encoding trimeric RBDs and NSP12 mitigates immune imprinting</b>. [PDF]

Mol Ther Nucleic Acids
De Chiara A, Giachino C, Pirillo MF, Campanile A, Pellino E, Gallinaro A, Froechlich G, Falce C, Scognamiglio A, Totaro S, Liguori MV, Peltrini R, De Simone A, Capone S, Pietro Z, Negri D, Cara A, Nicosia A, Sasso E.   +18 more
europepmc   +1 more source

Porcine reproductive and respiratory syndrome virus antagonizes the host restriction factor SHFL to sustain viral programmed ribosomal frameshifting and replication. [PDF]

J Virol
Bu K, Shi J, Ding J, Xu T, Li Q, Li C, Li Y.   +6 more
europepmc   +1 more source

Development of RNA Aptamers That Inhibit the RNA-Dependent RNA Polymerase Activity of SARS-CoV-2 Strains In Vitro. [PDF]

Int J Mol Sci
Song C, Lee SW.
europepmc   +1 more source

Fusion Strategy of DNA-Encoded Libraries Drives Discovery of Allosteric Inhibitors of SARS-CoV‑2 RdRp. [PDF]

JACS Au
Li L, Wang X, Ding P, Shen X, Hu H, Wang X, Jin R, Wu X, Zhang Y, Lu W, Yue J, Xu HE, Yin W, Xu Y, Lu X.   +14 more
europepmc   +1 more source

ZNF219 inhibits porcine epidemic diarrhea virus by degrading viral S2 protein. [PDF]

Virol Sin
Zhao W, Kong N, Lan D, Zhang Y, Liu H, Liu C, Qin W, Yang X, Liu T, Tong W, Yu H, Zheng H, Tong G, Xie S, Xing G, Shan T.   +15 more
europepmc   +1 more source

Porcine Mx1 protein inhibits porcine deltacoronavirus replication in vitro by disturbing the N-Nsp12 interaction

Porcine deltacoronavirus (PDCoV) is an emerging enteric pathogen with significant economic impact and potential zoonotic risk. The interplay between PDCoV and host innate immunity, particularly involving interferon-stimulated genes (ISGs), remains incompletely understood.
openaire   +1 more source

Nucleocapsid protein captures DDX5 and RNMT facilitating viral RNA synthesis and viral protein translation for coronavirus replication. [PDF]

mBio
Liu Y, Kong N, Yang X, Qin W, Wang Y, Wang C, Sun H, Wang J, Gao A, Zheng D, Tong W, Yu H, Zheng H, Tong G, Shan T.   +14 more
europepmc   +1 more source

Galectin 3-binding protein suppresses PRRSV replication via Cullin3-mediated ubiquitination degradation of non-structural protein 12. [PDF]

J Virol
Wang X, Zhang W, Zhang J, Li R, Zhang L, Yan N, Zhu J, Fu L, Wang Y.   +8 more
europepmc   +1 more source

Preferential remdesivir triphosphate incorporation by SARS-CoV-2 polymerase is altered to ATP by the S759A mutation. [PDF]

Commun Biol
Gordon CJ, Oliva MF, Lee HW, Goovaerts Q, De Wijngaert B, Götte M, Das K.   +6 more
europepmc   +1 more source