Results 101 to 110 of about 38,894 (153)

Polypeptide encoded by the -1 PRF signal of SARS-CoV-2 controls multiple enzymatic activities of the viral NiRAN domain. [PDF]

NAR Mol Med
Hsu HT, Cho CP, Lin CL, Chang KY.
europepmc   +1 more source

Slow PP_i release enhances fidelity of the SARS-CoV-2 RNA dependent RNA polymerase. [PDF]

J Biol Chem
Dangerfield TL, Marko I, Johnson KA.
europepmc   +1 more source

Reprogramming of lipid metabolism by ORF3a-induced microlipophagy enhances biogenesis of SARS-CoV-2 replication organelle. [PDF]

PLoS Pathog
Li Z, Hui X, Zheng M, He Z, Huai W, Ding B, Jin M, Qin Y, Chen M.   +8 more
europepmc   +1 more source

Dual-Site Inhibition of SARS-CoV-2 RNA-Dependent RNA Polymerase by Small Molecules Able to Block Viral Replication Identified through a Computer-Aided Drug Discovery Approach. [PDF]

ACS Infect Dis
Malune P, Iaconis D, Manelfi C, Giunta S, Emmolo R, Lunghini F, Paulis A, Talarico C, Corona A, Beccari AR, Tramontano E, Esposito F.   +11 more
europepmc   +1 more source

Differential Impact of Substrate Peptides on Interdomain Interactions in Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease. [PDF]

Comput Struct Biotechnol J
Fatima A, Biswas KH.
europepmc   +1 more source

SARS-CoV-2 Remdesivir Exposure Leads to Different Evolutionary Pathways That Converge in Moderate Levels of Drug Resistance. [PDF]

Viruses
Fernandez-Antunez C, Ryberg LA, Wang K, Pham LV, Mikkelsen LS, Fahnøe U, Hartmann KT, Jensen HE, Holmbeck K, Bukh J, Ramirez S.   +10 more
europepmc   +1 more source

Development of GFP-expressing infectious clones for PRRSV using TAR cloning for antiviral drug screening. [PDF]

Npj Viruses
Zhang M, Qian B, Kunec D, Veit M.
europepmc   +1 more source

Fisetin as an Antiviral Agent Targeting the RNA-Dependent RNA Polymerase of SARS-CoV-2: Computational Prediction and In Vitro Experimental Validation. [PDF]

Microorganisms
Hernández-Rodríguez X, Lira-Hernández FI, Reyes-Ruíz JM, Osuna-Ramos JF, Farfán-Morales CN, Calderón-Sandate DN, Castañeda-Delgado JE, León-Juárez M, Ángel RMD, Rivas-Santiago B, Noriega S, Cañedo-Figueroa DM, Montaño S, Santos-Mena AO, García-Herrera AC, De Jesús-González LA.   +15 more
europepmc   +1 more source

Optimization and comparison research on adaptive modularization BERT-SPAN model for named entity recognition of SARS-CoV-2 virus proteins. [PDF]

Sci Rep
Shi X, Fei Z, Nkhata A, Chen L, Chen Z, Chen H.   +5 more
europepmc   +1 more source

Broad-spectrum CRISPR-Cas13d-mediated strategy for combating human coronaviruses. [PDF]

Mol Ther Nucleic Acids
Yu Z, Hussein M, Bao Y, Alcalá-Lalinde A, Kroon PZ, Thuillier E, Zhang Z, Enjuanes L, Zuñiga S, Berkhout B, Herrera-Carrillo E.   +10 more
europepmc   +1 more source