Results 111 to 120 of about 38,142 (142)

A Phylogenetic Method Identifies Candidate Drivers of the Evolution of the SARS-CoV-2 Mutation Spectrum. [PDF]

Mol Biol Evol
Corbett-Detig R.
europepmc   +1 more source

Covalent inhibition of the SARS-CoV-2 NiRAN domain via an active-site cysteine. [PDF]

J Biol Chem
Hernandez G, Osinski A, Majumdar A, Eitson JL, Antczak M, Pawłowski K, Niederstrasser H, Servage KA, Posner B, Schoggins JW, Ready JM, Tagliabracci VS.   +11 more
europepmc   +1 more source

Evolution of Antiviral Drug Resistance in SARS-CoV-2. [PDF]

Viruses
Dinata R, Baindara P, Mandal SM.
europepmc   +1 more source

Unveiling the structural and functional implications of uncharacterized NSPs and variations in the molecular toolkit across arteriviruses. [PDF]

NAR Genom Bioinform
Rakesh S, Behera K, Krishnan A.
europepmc   +1 more source

Pre-existing and early cellular immune factors correlate with functionally complete protection against primary controlled human SARS-CoV-2 infection. [PDF]

Nat Commun
Wagstaffe HR, Thwaites RS, Sidhu JK, Lindeboom RGH, Kretschmer L, Worlock KB, Dratva LM, Huang A, Ascough S, Papargyris L, McKendry R, Collins AM, Xu J, Lemm NM, Killingley B, Kalinova M, Mann A, Catchpole A, Swadling L, Tsang JS, Maini MK, Noursadeghi M, Nikolić MZ, Teichmann SA, Openshaw PJM, Chiu C.   +25 more
europepmc   +1 more source

CRTC3 restricts SARS-CoV-2 replication and is antagonized by CREB. [PDF]

Virol Sin
Yang L, Zeng XT, Luo RH, Tang Y, Ren SX, Long XY, Fu XH, Zhang WJ, Ren HY, Zheng YT, Cheng W.   +10 more
europepmc   +1 more source

Identification of fidelity-determined residues of Porcine reproductive and respiratory syndrome virus through structural alignment. [PDF]

Virulence
Gao X, Zhang J, Gao P, Ge X, Zhang Y, Han J, Guo X, Zhou L, Yang H.   +8 more
europepmc   +1 more source

SARS-CoV-2 resistance analyses from the Phase 3 PINETREE study of remdesivir treatment in nonhospitalized participants. [PDF]

Antimicrob Agents Chemother
Rodriguez L, Lee HW, Li J, Martin R, Han D, Xu S, Moshiri J, Peinovich N, Camus G, Perry JK, Hyland RH, Porter DP, Abdelghany M, Götte M, Hedskog C.   +14 more
europepmc   +1 more source

Mechanistic insights into the activity of SARS-CoV-2 RNA polymerase inhibitors using single-molecule FRET. [PDF]

Nucleic Acids Res
Groves D, Cunnison R, McMahon A, Fan H, Sharps J, Deng A, Keown JR, Fodor E, Robb NC.   +8 more
europepmc   +1 more source

The C-terminal Domain of SARS-CoV-2 nsp8 is a Molten Globule in the Absence of Binding Partners. [PDF]

J Mol Biol
Kurauskas V, Tonelli M, Kirchdoerfer RN, Henzler-Wildman K.   +3 more
europepmc   +1 more source