Results 101 to 110 of about 3,842 (144)

Modulation of Host Innate Immune Response by Highly Pathogenic Human Coronaviruses during Viral Infection. [PDF]

J Microbiol Biotechnol
Kim YJ, Lee SJ, Lee W, Kim SJ, Ahn DG.
europepmc   +1 more source

ATPase-dependent duplex nucleic acid unwinding by SARS-CoV-2 nsP13 relies on facile binding and translocation along single-stranded nucleic acid. [PDF]

J Biol Chem
Park J, Jeong YJ, Chauhan K, Koh HR, Kim DE.   +4 more
europepmc   +1 more source

Myricetin-bound crystal structure of the SARS-CoV-2 helicase NSP13 facilitates the discovery of novel natural inhibitors. [PDF]

Acta Crystallogr D Struct Biol
Kloskowski P, Neumann P, Kumar P, Berndt A, Dobbelstein M, Ficner R.   +5 more
europepmc   +1 more source

Reprogramming of lipid metabolism by ORF3a-induced microlipophagy enhances biogenesis of SARS-CoV-2 replication organelle. [PDF]

PLoS Pathog
Li Z, Hui X, Zheng M, He Z, Huai W, Ding B, Jin M, Qin Y, Chen M.   +8 more
europepmc   +1 more source

SARS-CoV-2 point mutations are over-represented in terminal loops of RNA stem-loop structures that can be resolved by Nsp13 helicase in a unique manner with respect to nucleotide dependence. [PDF]

Nucleic Acids Res
Dumm AJ, Zheng AY, Butler TJ, Kulikowicz T, George JC, Bombard PT, Sommers JA, Ding J, Brosh RM.   +8 more
europepmc   +1 more source

Monitoring SARS-CoV-2 Nsp13 helicase binding activity using expanded genetic code techniques. [PDF]

RSC Chem Biol
Lundrigan E, Hum C, Ahmed N, Pezacki JP.
europepmc   +1 more source

Au(I)-based compounds inhibit nsp14/nsp10 and nsp13 (helicase) to exert anti-SARS-CoV-2 properties. [PDF]

J Biol Inorg Chem
Chen J, Wei X, Chan CL, Tang K, Yuan S, Li H, Sun H.   +6 more
europepmc   +1 more source

Structure-Activity Relationships of New 1-Aryl-1H-Indole Derivatives as SARS-CoV-2 Nsp13 Inhibitors. [PDF]

ChemMedChem
Madia VN, Emmolo R, Patacchini E, Amatore D, Maloccu S, Ialongo D, Albano A, Ruggieri G, Cara E, Zarbo L, Messore A, De Santis R, Amoroso A, Lista F, Esposito F, Tramontano E, Corona A, Di Santo R, Costi R.   +18 more
europepmc   +1 more source

Unwinding process of DNA/RNA quadruplexes by proteins under label-free nanopore monitoring. [PDF]

Nucleic Acids Res
Ren M, Weng T, Liang L, Chen X, Liu D, Fang S, Tian R, Xie W, Wang L, Wang D, Zeng C.   +10 more
europepmc   +1 more source

How Can Plant-Derived Natural Products and Plant Biotechnology Help Against Emerging Viruses? [PDF]

Int J Mol Sci
Zahmanova G, Takova K, Tonova V, Minkov I, Barbolov M, Nedeva N, Vankova D, Ivanova D, Kiselova-Kaneva Y, Lukov GL.   +9 more
europepmc   +1 more source