Results 101 to 110 of about 12,023 (208)

STRN3-NTRK1: A Novel NTRK1 Oncogenic Fusion in a Patient with Lung Adenocarcinoma [PDF]

Journal of Thoracic Oncology, 2020
Rongguo Lu, Chuang Qi, Mingzhe Xiao, Shangli Cai, Mingfeng Zheng   +4 more
openaire   +1 more source

NTRK amplification occurs frequently in pan-TRK immunopositive dedifferentiated liposarcomas

Pathology and Oncology Research
The neurotrophic tyrosine kinase receptor (NTRK) gene family is of rising importance as their fusions are oncogenic, and specific target drugs are available to inhibit the chimera proteins.
Zoltán Lippai, Gergő Papp, Károly Szuhai, Johanna Sápi, Katalin Dezső, Zoltán Sápi   +5 more
doaj   +1 more source

c.1810C>T Polymorphism of NTRK1 Gene is associated with reduced Survival in Neuroblastoma Patients

BMC Cancer, 2009
Background TrkA (encoded by NTRK1 gene), the high-affinity tyrosine kinase receptor for neurotrophins, is involved in neural crest cell differentiation.
Chybicka Alicja, Perek Danuta, Balcerska Anna, Ziętkiewicz Szymon, Iżycka-Świeszewska Ewa, Tonini Gian, Scaruffi Paola, Drożynska Elżbieta, Lipska Beata S, Biernat Wojciech, Limon Janusz   +10 more
doaj   +1 more source

The Autocrine Impact of Nerve Growth Factor on Sheep Uterine Epithelial Cells

Cells
Nerve growth factor (NGF) plays a critical role in reproduction through paracrine and endocrine mechanisms. However, its autocrine effects on uterine receptivity and inflammatory pathways remain unknown.
Gabriella Guelfi, Rolando Pasquariello, Cecilia Dall’Aglio, Francesca Mercati, Chiara Suvieri, Carmela Conte, Camilla Capaccia, Marcelo Ratto, Margherita Maranesi   +8 more
doaj   +1 more source

Algebraic and Topological Indices of Molecular Pathway Networks in Human Cancers [PDF]

, 2014
Protein-protein interaction networks associated with diseases have gained prominence as an area of research. We investigate algebraic and topological indices for protein-protein interaction networks of 11 human cancers derived from the Kyoto Encyclopedia
Hinow, Peter, Rietman, Edward A., Tuszynski, Jack A.   +2 more
core  

Clinical and genetic characteristics of three patients with congenital insensitivity to pain with anhidrosis: Case reports and a review of the literature

Molecular Genetics & Genomic Medicine
Background Congenital insensitivity to pain with anhidrosis (CIPA) is an extremely rare autosomal recessive disorder caused by loss‐of‐function mutations of the NTRK1 gene, affecting the autonomic and sensory nervous system.
Jun Hee Cho, Soojin Hwang, Yoon Hae Kwak, Mi‐Sun Yum, Go Hun Seo, June‐Young Koh, Young Seok Ju, Ji‐Hee Yoon, Minji Kang, Hyo‐Sang Do, Soyoung Kim, Gu‐Hwan Kim, Hyunwoo Bae, Beom Hee Lee   +13 more
doaj   +1 more source

Atypical Presentation of Congenital Insensitivity to Pain With Anhidrosis Leading to Diagnostic Odyssey

Molecular Genetics & Genomic Medicine
Background Congenital insensitivity to pain with anhidrosis (CIPA) (OMIM 256800) is a rare autosomal‐recessive condition, also known as hereditary sensory and autonomic neuropathy type IV (HSAN‐IV). The most commonly reported features include anhidrosis,
Tomoyasu Higashimoto, Martin E. Garber, Lauren Hipp, Jenna Damon, Qing Li   +4 more
doaj   +1 more source

Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation [PDF]

, 2004
Culp, Lloyd A, Edsjö, Anders,, Karlsson, Jenny,, Lund University., Nilsson, Helén,, Pattyn, Filip, Påhlman, Sven,, Speleman, Frank, Vandesompele, Jo   +8 more
core   +2 more sources

Peran Mutasi B-RAF Dalam Kontroversi Tindakan Bedah Pada Penatalaksanaan Karsinoma Tiroid Papilifer [PDF]

, 2011
Karsinoma tiroid papilifer adalah jenis karsinoma tiroid diferensiasi baik yang paling banyak ditemukan. Tingkat pertumbuhannya lambat, prognosis baik, dan diagnosis dapat ditegakkan dengan pemeriksaan sitopatologi karena menunjukkan Perubahan sel yang ...
Ahmad, D. (Dimyati)
core  

Predisposing deleterious variants in the cancer-associated human kinases in the global populations.

PLoS ONE
Human kinases play essential and diverse roles in the cellular activities of maintaining homeostasis and growth. Genetic mutations in the genes encoding the kinases (or phosphotransferases) have been linked with various types of cancers.
Salman Ahmed Khan, Misbah Anwar, Atia Gohar, Moom R Roosan, Daniel C Hoessli, Ambrina Khatoon, Muhammad Shakeel   +6 more
doaj   +1 more source