Results 71 to 80 of about 9,316 (206)
STRN3-NTRK1: A Novel NTRK1 Oncogenic Fusion in a Patient with Lung Adenocarcinoma [PDF]
Rongguo Lu +4 more
openaire +1 more source
Histiocytosis development and clinical variation through the lens of genomics
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps +3 more
wiley +1 more source
Kaplan–Meier survival curves comparing two‐cycle versus three‐cycle neoadjuvant sintilimab plus chemotherapy. (A) Disease‐free survival (DFS). (B) Overall survival (OS). CI, confidence interval; HR, hazard ratio; NR, not reached. ABSTRACT The optimal number of neoadjuvant chemoimmunotherapy cycles for resectable non‐small cell lung cancer (NSCLC ...
Miner Shao +13 more
wiley +1 more source
More Than a Birthmark? A Growing Pediatric Skin Lesion
JEADV Clinical Practice, EarlyView.
Shatha Ahmad Al Hajjaj +2 more
wiley +1 more source
Radioiodine‐refractory differentiated thyroid cancer (RAIR‐DTC) management now spans selective kinase inhibitors, MAPK‐pathway redifferentiation, VEGFR multikinase TKIs, and biomarker‐driven immunotherapy. We propose a three‐axis decision framework integrating molecular driver, evidence level, and patient dimension to guide individualized treatment ...
Yamin Li, Zuoxiang He
wiley +1 more source
Supplementary FigureS1: Sensitivity of TPM3†NTRK1 Ba/F3 clones to various NTRK1 inhibitors; Supplementary FigureS2: Sensitivity of TPM3†NTRK1 G595R mutant Ba/F3 cells to various NTRK1 inhibitors; Supplementary Figure S3: Sensitivity of TPM3â ...
Naoya Fujita (448838) +5 more
core +1 more source
Background: Congenital insensitivity to pain with anhidrosis (CIPA), a rare autosomal recessive sensory neuropathy, was caused mainly by biallelic mutations in the NTRK1 gene.
Hua-Ying Hu (11797217) +10 more
core +1 more source
MEIS1::NCOA2 Rearranged Spindle Cell Neoplasm of Vulva With Unusual Low‐Grade Morphology
ABSTRACT MEIS1::NCOA2 is a recurrent gene fusion that has been predominantly identified in primitive sarcomas arising within the genitourinary and gynecological tracts. Since its initial description in 2018, an increasing number of cases have been reported, further defining the clinicopathological spectrum of this entity.
Pinki Soni +6 more
wiley +1 more source
Abstract Recurrent fusions involving FGFR1‐4 genes have been previously described in rare subsets of mostly benign chondroid and mesenchymal neoplasms involving bone and soft tissue. However, a more comprehensive analysis of sarcomas associated with FGFR fusions, including their incidence and histotypes, has not been performed.
Maximus CF Yeung +4 more
wiley +1 more source
Background: Congenital insensitivity to pain with anhidrosis (CIPA), a rare autosomal recessive sensory neuropathy, was caused mainly by biallelic mutations in the NTRK1 gene.
Hua-Ying Hu (11797217) +10 more
core +1 more source

