Results 51 to 60 of about 1,784 (124)
Cell Proliferation, EarlyView.We designed a framework for screening clinical drug combinations with anti‐hepatocellular carcinoma (HCC) activity, comprising four parts: primary screening, single‐cell screening, functional validation, and mechanism research. High‐throughput single‐cell screening identifies HY (HHT and YM155) as a potent anti‐HCC drug combination, validated by in ...
Mengmeng Jiang +12 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 2, March 2026.The study found that MAMP‐1 can alleviate lung injury by modulating the TLR4 signaling pathway to suppress LPS‐induced inflammation and promote cholesterol reverse transport. ABSTRACT Sepsis‐associated acute lung injury (SALI) significantly jeopardizes the health and survival prospects of neonates.
Shimei Lu +8 more
wiley +1 more source
Why enveloped viruses need cores -- the contribution of a nucleocapsid core to viral budding
, 2017 During the alphavirus lifecycle, a nucleocapsid core buds through the cell membrane to acquire an outer envelope of lipid membrane and viral glycoproteins. However, the presence of a nucleocapsid core is not required for assembly of infectious particles.
Hagan, Michael F. +2 more
core +1 more source
Roles of Cross-Membrane Transport and Signaling in the Maintenance of Cellular Homeostasis [PDF]
, 2016 Organelles allow specialized functions within cells to be localized, contained and independently regulated. This separation is oftentimes achieved by selectively permeable membranes, which enable control of molecular transport, signaling between ...
Inchul Cho, Joe Swift, Mark R. Jackson
core +2 more sources
Vesicular Nucleo-Cytoplasmic Transport—Herpesviruses as Pioneers in Cell Biology
Viruses, 2016 Herpesviruses use a vesicle-mediated transfer of intranuclearly assembled nucleocapsids through the nuclear envelope (NE) for final maturation in the cytoplasm.
Thomas C. Mettenleiter
doaj +1 more source
The tasiR‐ARF pathway in plants: origin, functions, and interplay of miR‐390, tasiRNAs and ARF3
Plant Biology, Volume 28, Issue 2, Page 328-344, March 2026.Trans‐acting small interfering RNAs that silence a subset of Auxin Response Factors are crucial for plant growth, developmental timing, proper organ patterning, and coping with stress. Abstract Trans‐acting small interfering RNA (tasiRNAs) are a special type of endogenous small RNAs (sRNAs) found only in plants.
B. A. López‐Ruiz +4 more
wiley +1 more source
Solar‐Blind Ultraviolet Photodetectors Based on Two‐Dimensional Materials and Their Heterostructures
Advanced Physics Research, Volume 5, Issue 2, February 2026.Solar‐blind ultraviolet photodetectors are crucial for diverse applications. This review comprehensively summarizes recent advances using two‐dimensional materials and their heterostructures, which offer tunable bandgaps, flexibility, and no lattice‐matching constraints.
Yu Lu +7 more
wiley +1 more source
Analysis of the nuclear egress complex of mouse cytomegalovirus [PDF]
, 2007 Herpesvirus infections are usually asymptomatic or associated with mild symptoms. Fatal diseases are seen in immune suppressed and immune incompetent individuals. Although herpesviruses are of emerging medical importance nowadays an infection only can be
Loetzerich, Mark
core
Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling
Brain and Behavior, Volume 16, Issue 2, February 2026.Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu +1 more
wiley +1 more source
A novel secreted protein, MYR1, is central to Toxoplasma’s manipulation of host cells [PDF]
, 2016 The intracellular protozoan Toxoplasma gondii dramatically reprograms the transcriptome of host cells it infects, including substantially up-regulating the host oncogene c-myc.
Bednarski, Jeffrey J +9 more
core +3 more sources