Results 41 to 50 of about 1,828,054 (294)
Viruses, 2014 Previously we reported that nuclear export of both unspliced and spliced murine leukemia virus (MLV) transcripts depends on the nuclear export factor (NXF1) pathway.
Toshie Sakuma +2 more
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Regulation of Stat3 nuclear export [PDF]
Journal of Clinical Investigation, 2003 Stat3 is the most pleiotropic member of the signal transducer and activator of transcription (STAT) family of transcription factors and mediates pivotal responses for the cytokine family. In resting cells, STATs, including Stat3, reside largely in the cytoplasm.
Samita, Bhattacharya +1 more
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Calreticulin Is a Receptor for Nuclear Export [PDF]
The Journal of Cell Biology, 2001 In previous work, we used a permeabilized cell assay that reconstitutes nuclear export of protein kinase inhibitor (PKI) to show that cytosol contains an export activity that is distinct from Crm1 (Holaska, J.M., and B.M. Paschal. 1995. Proc. Natl. Acad. Sci. USA. 95: 14739–14744). Here, we describe the purification and characterization of the activity
J M, Holaska +5 more
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Nuclear dynamics: Formation of bodies and trafficking in plant nuclei
Frontiers in Plant Science, 2022 The existence of the nucleus distinguishes prokaryotes and eukaryotes. Apart from containing most of the genetic material, the nucleus possesses several nuclear bodies composed of protein and RNA molecules.
Eduardo Muñoz-Díaz +3 more
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mRNA nuclear export at a glance [PDF]
Journal of Cell Science, 2009 Eukaryotic gene expression is controlled by multiple mechanisms, and its regulation is central for physiological responses to extracellular and intracellular signals. An essential step in this process involves the movement of mRNA transcripts from the site of synthesis in the nucleus to ...
Sean R, Carmody, Susan R, Wente
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RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1 [PDF]
, 2015 Controlled transport of macromolecules between the cytoplasm and nucleus is essential for homeostatic regulation of cellular functions. For instance, gene expression entails coordinated nuclear import of transcriptional regulators to activate ...
Vartiainen, Maria K. +5 more
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KLF4 Nuclear Export Requires ERK Activation and Initiates Exit from Naive Pluripotency
Stem Cell Reports, 2018 Summary: Cooperative action of a transcription factor complex containing OCT4, SOX2, NANOG, and KLF4 maintains the naive pluripotent state; however, less is known about the mechanisms that disrupt this complex, initiating exit from pluripotency.
Navroop K. Dhaliwal +4 more
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tRNAs promote nuclear import of HIV-1 intracellular reverse transcription complexes [PDF]
, 2006 Infection of non-dividing cells is a biological property of HIV-1 crucial for virus transmission and AIDS pathogenesis. This property depends on nuclear import of the intracellular reverse transcription and pre-integration complexes (RTCs/PICs).
Zaitseva Lyubov +8 more
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Nuclear Export of Messenger RNA [PDF]
Genes, 2015 Transport of messenger RNA (mRNA) from the nucleus to the cytoplasm is an essential step of eukaryotic gene expression. In the cell nucleus, a precursor mRNA undergoes a series of processing steps, including capping at the 5' ends, splicing and cleavage/polyadenylation at the 3' ends.
openaire +2 more sources
Analysis of the Activity of Nuclear Export Signals Using Fluorescent BSA Conjugates
BioTechniques, 2002 Here we demonstrate that fluorescein-labeled BSA conjugated with a mixture of nuclear import and export signals can be used to evaluate export activity.
Carl M. Feldherr, Debra Akin
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