Results 21 to 30 of about 1,828,054 (294)
SRAG Functions as a New mRNA Export Co-adaptor [PDF]
, 2012 DEAD box RNA helicases play important roles in many cellular processes including splicing, mRNA export and translation. The two domains of many DEAD box RNA helicases adopt radically different conformations according to whether they are ...
Chang, Chung-Te
core +6 more sources
Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex
Nature Communications, 2023 Nuclear export of influenza A virus (IAV) mRNAs occurs through the nuclear pore complex (NPC). Using the Auxin-Induced Degron (AID) system to rapidly degrade proteins, we show that among the nucleoporins localized at the nucleoplasmic side of the NPC ...
Prasanna Bhat +18 more
doaj +1 more source
The Ebola Virus Interferon Antagonist VP24 Undergoes Active Nucleocytoplasmic Trafficking
Viruses, 2021 Viral interferon (IFN) antagonist proteins mediate evasion of IFN-mediated innate immunity and are often multifunctional, with distinct roles in viral replication.
Angela R. Harrison +3 more
doaj +1 more source
The nuclear pore complex : its role in chromatin structure and RNA export [PDF]
, 2015 Epigenetic regulation of gene expression is a relatively new and rapidly developing research field. It studies the mechanisms of regulation of gene expression, which although heritable, occur independently of changes in the DNA sequence and certainly aid
Hristova, Emilia
core +1 more source
IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs
eLife, 2017 Expression of inflammatory genes is determined in part by post-transcriptional regulation of mRNA metabolism but how stimulus- and transcript-dependent nuclear export influence is poorly understood.
Hao Zhou +25 more
doaj +1 more source
An Endoribonuclease Functionally Linked to Perinuclear mRNP Quality Control Associates with the Nuclear Pore Complexes [PDF]
, 2009 Nuclear mRNA export is a crucial step in eukaryotic gene expression, which is in yeast coupled to cotranscriptional messenger ribonucleoprotein particle ( mRNP) assembly and surveillance.
Attila Rácz +17 more
core +1 more source
Nop53p is required for late 60S ribosome subunit maturation and nuclear export in yeast [PDF]
, 2005 We report that Ypl146cp/Nop53p is associated with pre-60S ribosomal complexes and localized to the nucleolus and nucleoplasm. in cells depleted of Nop53p synthesis of the rRNA components of the 60S ribosomal subunit is severely inhibited, with strikingly
Tollervey, D, Thomson, E
core +1 more source
PLoS Pathogens, 2011 The hTREX complex mediates cellular bulk mRNA nuclear export by recruiting the nuclear export factor, TAP, via a direct interaction with the export adaptor, Aly.
Brian R Jackson +9 more
doaj +1 more source
iScience, 2021 Summary: Heterogeneous nuclear ribonucleoproteins (hnRNPs) play critical roles in the nuclear export, splicing, and sensing of RNA. However, the role of heterogeneous nuclear ribonucleoprotein A/B (hnRNPAB) is poorly understood.
Xingbo Wang +7 more
doaj +1 more source
Nuclear Import and Export Signals of Human Cohesins SA1/STAG1 and SA2/STAG2 Expressed in Saccharomyces cerevisiae [PDF]
, 2012 Background: Human SA/STAG proteins, homologues of the yeast Irr1/Scc3 cohesin, are the least studied constituents of the sister chromatid cohesion complex crucial for proper chromosome segregation.
Jurek, Marta +27 more
core +1 more source