Results 11 to 20 of about 315,054 (297)
YTHDC1 phase separation drives the nuclear export of m6A-modified lncNONMMUT062668.2 through the transport complex SRSF3–ALYREF–XPO5 to aggravate pulmonary fibrosis [PDF]
Cell Death and DiseaseFibroblast-to-myofibroblast differentiation is the main cytopathologic characteristic of pulmonary fibrosis. However, its underlying molecular mechanism remains poorly understood.
Shengjun Chen +11 more
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Data Augmentation of X-ray Images for Automatic Cargo Inspection of Nuclear Items
Sensors, 2023 As part of establishing a management system to prevent the illegal transfer of nuclear items, automatic nuclear item detection technology is required during customs clearance. However, it is challenging to acquire X-ray images of major nuclear items (e.g.
Haneol Jang +3 more
doaj +1 more source
Genes & Development, 1998 RNA export is the process by which RNAs are transported to the cytoplasm after synthesis, processing, and RNP assembly within the nucleus. The primary focus of this review is mRNA export with particular attention paid to the yeast Saccharomyces cerevisiae.
F, Stutz, M, Rosbash
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Biology of the Cell, 2004 Abstract A defining feature of eukaryotic cells is the presence of a nuclear envelope separating transcription and DNA replication in the nucleus from the site of protein synthesis in the cytoplasm. The regulation of gene expression relies in part on the controlled exchange of molecules between these two compartments.
Rodriguez, Manuel S +2 more
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Genotoxic agents promote the nuclear accumulation of annexin A2: role of annexin A2 in mitigating DNA damage [PDF]
, 2012 Annexin A2 is an abundant cellular protein that is mainly localized in the cytoplasm and plasma membrane, however a small population has been found in the nucleus, suggesting a nuclear function for the protein.
A Hofmann +58 more
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iScience, 2023 Summary: We present a study on the nuclear export efficiency and time of pre-ribosomal subunits in live mammalian cells, using high-speed single-molecule tracking and single-molecule fluorescence resonance energy transfer techniques.
Samuel L. Junod +5 more
doaj +1 more source
Cells, 2020 In humans, (A549) cells impaired H9N2 virus nuclear export of the ribonucleoprotein (RNP) complex contrasted with the early and efficient nuclear export of the H1N1/WSN and pH1N1 virus RNP complexes.
Sriram Kumar +6 more
doaj +1 more source
FEBS Letters, 2001 Export of mRNA through nuclear pore complexes (NPC) is preceded by multiple and well coordinated processing steps, resulting in the formation of an export competent ribonucleoprotein complex (mRNP). Numerous factors involved in the translocation of the mRNP through the NPC and its release into the cytoplasm have been isolated mainly through genetic ...
Zenklusen, D, Stutz, Françoise
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The deubiquitylase Ubp15 couples transcription to mRNA export
eLife, 2020 Nuclear export of messenger RNAs (mRNAs) is intimately coupled to their synthesis. pre-mRNAs assemble into dynamic ribonucleoparticles as they are being transcribed, processed, and exported.
Fanny Eyboulet +3 more
doaj +1 more source
Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex
Nature Communications, 2023 Nuclear export of influenza A virus (IAV) mRNAs occurs through the nuclear pore complex (NPC). Using the Auxin-Induced Degron (AID) system to rapidly degrade proteins, we show that among the nucleoporins localized at the nucleoplasmic side of the NPC ...
Prasanna Bhat +18 more
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