Results 11 to 20 of about 1,828,054 (294)

Nuclear mRNA export

Acta Biochimica et Biophysica Sinica
In eukaryotic cells, gene expression begins with transcription in the nucleus, followed by the maturation of messenger RNAs (mRNAs). These mRNA molecules are then exported to the cytoplasm through the nuclear pore ...
Chen Suli, Jiang Qingyi, Fan Jing, Cheng Hong   +3 more
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Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals

eLife, 2017
Nuclear export receptor CRM1 binds highly variable nuclear export signals (NESs) in hundreds of different cargoes. Previously we have shown that CRM1 binds NESs in both polypeptide orientations (Fung et al., 2015).
Ho Yee Joyce Fung, Szu-Chin Fu, Yuh Min Chook   +2 more
doaj   +3 more sources

Nuclear RNA export in yeast [PDF]

FEBS Letters, 1999
Eukaryotic cells massively exchange macromolecules (proteins and RNAs) between the nucleus and cytoplasm through the nuclear pore complexes. Whereas a mechanistic picture emerges of how proteins are imported into and exported from the nucleus, less is ...
Sträßer, Katja, Katja Sträßer, Ed Hurt, Hurt, Ed   +3 more
core   +4 more sources

Nuclear export of proteins in plants: AtXPO1 is the export receptor for leucine-rich nuclear export signals in Arabidopsis thaliana [PDF]

The Plant Journal, 1999
Haasen D, Köhler C, Neuhaus G, Merkle T. Nuclear export of proteins in plants: AtXPO1 is the export receptor for leucine-rich nuclear export signals in Arabidopsis thaliana. The Plant Journal.
Haasen, D., Neuhaus, G., Merkle, Thomas, Köhler, C., Merkle, T.   +4 more
core   +5 more sources

International Nuclear Law and Nuclear Export Controls

International Journal of Nuclear Law, 2011
Evaluating the effectiveness of nuclear export controls necessitates a serious analysis of the circumstances in which they function and the elements that give them force, such as the international non-proliferation legal context, legal aspects of the ...
Andrea Viski, VISKI, Andrea
core   +3 more sources

Nuclear export of circular RNA

Nature
Circular RNAs (circRNAs), which are increasingly being implicated in a variety of functions in normal and cancerous cells1-5, are formed by back-splicing of precursor mRNAs in the nucleus6-10.
Dredge, BK, Deans, A.J., Li, W., Pillman, K.A., Hamilton, WB, Desogus, J, Desogus, J., Goodall, GJ, Wickramasinghe, V.O., Pillman, KA, Bert, A.G., Deans, AJ, Bert, AG, Carey, KT, Liu, D., Toubia, J, Williams, T, Dredge, B.K., Murphy, V., Toubia, J., Carey, K.T., Chao, JA, Ngo, L.H., Liu, D, Wickramasinghe, VO, Williams, T., Hamilton, W.B., Li, W, Chao, J.A., Goodall, G.J., Murphy, V, Ngo, LH   +31 more
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A Supraphysiological Nuclear Export Signal Is Required for Parvovirus Nuclear Export [PDF]

Molecular Biology of the Cell, 2008
CRM1 exports proteins that carry a short leucine-rich peptide signal, the nuclear export signal (NES), from the nucleus. Regular NESs must have low affinity for CRM1 to function optimally. We previously generated artificial NESs with higher affinities for CRM1, termed supraphysiological NESs.
Engelsma, Dieuwke, Valle, Noelia, Fish, Alexander, Salomé, Nathalie, Almendral, José M., Fornerod, Maarten   +5 more
openaire   +3 more sources

Nuclear export of RNA [PDF]

Biology of the Cell, 2004
Abstract A defining feature of eukaryotic cells is the presence of a nuclear envelope separating transcription and DNA replication in the nucleus from the site of protein synthesis in the cytoplasm. The regulation of gene expression relies in part on the controlled exchange of molecules between these two compartments.
Rodriguez, Manuel S, Dargemont, Catherine, Stutz, Françoise   +2 more
openaire   +3 more sources

Nuclear RNA export [PDF]

Genes & Development, 1998
RNA export is the process by which RNAs are transported to the cytoplasm after synthesis, processing, and RNP assembly within the nucleus. The primary focus of this review is mRNA export with particular attention paid to the yeast Saccharomyces cerevisiae.
Stutz F, Rosbash M
openaire   +3 more sources

Nuclear export of mRNA [PDF]

FEBS Letters, 2001
Export of mRNA through nuclear pore complexes (NPC) is preceded by multiple and well coordinated processing steps, resulting in the formation of an export competent ribonucleoprotein complex (mRNP). Numerous factors involved in the translocation of the mRNP through the NPC and its release into the cytoplasm have been isolated mainly through genetic ...
Zenklusen, D, Stutz, Françoise
openaire   +4 more sources