Results 11 to 20 of about 17,074,019 (238)
Immunomodulatory effects of curcumin on receptor activator of nuclear factor-kappa B ligand in periodontitis [PDF]
Mediterranean Journal of Pharmacy and Pharmaceutical SciencesPeriodontitis is a chronic inflammatory disease of the tooth-supporting structures, often causing alveolar bone loss due to increased osteoclast activity mediated by receptor activator of nuclear factor-kappa B ligand.
Fiki Muhammad Ridho
doaj +6 more sources
How to Inhibit Nuclear Factor-Kappa B Signaling: Lessons from Poxviruses
Pathogens, 2022 The Nuclear Factor-kappa B (NF-κB) family of transcription factors regulates key host inflammatory and antiviral gene expression programs, and thus, is often activated during viral infection through the action of pattern-recognition receptors and ...
Joshua B. Reus +2 more
doaj +2 more sources
Nuclear factor kappa-B and the heart [PDF]
Journal of the American College of Cardiology, 2001 Nuclear factor kappa-B (NFkappaB), a redox-sensitive transcription factor regulating a battery of inflammatory genes, has been indicated to play a role in the development of numerous pathological states. Activation of NFkappaB induces gene programs leading to transcription of factors that promote inflammation, such as leukocyte adhesion molecules ...
Valen, Guro +2 more
openaire +3 more sources
Tumour Necrosis Factor-alpha and Nuclear Factor-kappa B Gene Variants in Sepsis
Balkan Medical Journal, 2018 Background: The humoral system is activated and various cytokines are released due to infections in tissues and traumatic damage. Nuclear factor-kappa B dimers are encoded by nuclear factor-kappa B genes and regulate transcription of several crucial ...
Leyla Acar +3 more
doaj +2 more sources
Nuclear Factor Kappa B Pathway and human cancer therapeutics [PDF]
, 2009 A thesis submitted in partial fufilment of the requirements of the University of Wolverhampton for the degree of Doctor of PhilosophyCancer is one of the major causes of morbidity in the world.
Guo, Xiaoxia
core +3 more sources
Heliyon, 2022 Context: Torin2 has various pharmacological properties. However, its anti-inflammatory activity has not been reported. Objective: This study focused on the potential anti-inflammatory properties of Torin2 in lipopolysaccharide (LPS)-evoked RAW264.7 ...
Shanshan Wei +5 more
doaj +1 more source
Endurance exercise training suppresses myostatin upregulation and nuclear factor-kappa B activation in a mouse model of Parkinson's disease [PDF]
Veterinary World, 2022 Background and Aim: Muscle atrophy is common in Parkinson's disease (PD). Although myostatin has been implicated in muscle atrophy, its expression in PD skeletal muscle has not been investigated.
Nour S. Erekat, Muhammed D. Al-Jarrah
doaj +1 more source
Nuclear factor-kappa B pathways in Drosophila [PDF]
Oncogene, 2006 The nuclear factor kappa B (NF-kappaB) pathways in Drosophila are multi-component pathways, as in vertebrates, that regulate the expression of many genes responsible for the formation of dorsal-ventral polarity in the early embryo, the innate immune response to infection with Gram- negative and positive bacteria and fungi, the cellular immune response ...
S, Minakhina, R, Steward
openaire +2 more sources
Exploring new pathways in endocrine-resistant breast cancer
Exploration of Targeted Anti-tumor Therapy, 2022 The most common breast cancer (BC) subtypes are hormone-dependent, being either estrogen receptor-positive (ER+), progesterone receptor-positive (PR+), or both, and altogether comprise the luminal subtype.
Inês Soares de Pinho +6 more
doaj +1 more source
The Effect of Open Reading Frame 3 of Hepatitis E virus on Cellular NF-κB Activity [PDF]
Basrah Journal of Veterinary Research, 2023 NF-B (Nuclear Factor Kappa B) is a crucial transcription factor that is essential for host survival during pathogen infection in animal and human. Therefore, it has been a main goal for numerous pathogens to modify cellular NF-κB activity to create
Rana Abdulnabi +2 more
doaj +1 more source