Results 151 to 160 of about 1,676,612 (335)

Anchoring of Heterochromatin to the Nuclear Lamina Reinforces Dosage Compensation-Mediated Gene Repression

open access: yesPLoS Genetics, 2016
Higher order chromosome structure and nuclear architecture can have profound effects on gene regulation. We analyzed how compartmentalizing the genome by tethering heterochromatic regions to the nuclear lamina affects dosage compensation in the nematode ...
Martha J Snyder   +6 more
semanticscholar   +1 more source

Thermal Processing Creates Water‐Stable PEDOT:PSS Films for Bioelectronics

open access: yesAdvanced Materials, Volume 37, Issue 13, April 2, 2025.
Instead of using chemical cross–linkers, it is shown that PEDOT:PSS thin films for bioelectronics become water‐stable after a simple heat treatment. The heat treatment is compatible with a range of rigid and elastomeric substrates and films are stable in vivo for >20 days.
Siddharth Doshi   +16 more
wiley   +1 more source

Perturbations in 3D genome organization can promote acquired drug resistance

open access: yesCell Reports, 2023
Summary: Acquired drug resistance is a major problem in the treatment of cancer. hTERT-immortalized, untransformed RPE-1 cells can acquire resistance to Taxol by derepressing the ABCB1 gene, encoding for the multidrug transporter P-gP.
Anna G. Manjón   +17 more
doaj  

Iodine‐Doped Sodium Vanadate Cathode for Improved Zn Ion Diffusion Kinetics

open access: yesAdvanced Materials, EarlyView.
An iodine‐doping strategy is developed to modify the Na2V6O16·3H2O cathode for aqueous zinc‐ion batteries, effectively reducing the electrostatic interaction between zinc ions and the host structure. This modification enables faster diffusion and higher storage capacity of zinc ions. Abstract The electrostatic interaction between zinc ions and the host
Xinyue Hu   +13 more
wiley   +1 more source

Identifying Novel Transcriptional and Epigenetic Features of Nuclear Lamina-associated Genes

open access: yesScientific Reports, 2017
Because a large portion of the mammalian genome is associated with the nuclear lamina (NL), it is interesting to study how native genes resided there are transcribed and regulated.
Feinan Wu, Jie Yao
semanticscholar   +1 more source

Pushing the envelope: Developmental regulation by the nuclear lamina [PDF]

open access: yesDevelopmental Dynamics, 2008
AbstractA surprising realization in recent years was that proteins of the nuclear lamina directly regulate gene expression and cell differentiation. Presented here are examples that highlight the diverse roles these proteins can inhabit. Accompanying the primer is a discussion of current topics in the field with nuclear lamina experts Colin Stewart, Ph.
openaire   +3 more sources

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

open access: yesAdvanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang   +3 more
wiley   +1 more source

Exceptional Thermal Conductivity in Printed Dielectrics through Compositional and Microstructural Design

open access: yesAdvanced Materials, EarlyView.
A multi‐generational compositional design creates a printable low‐loss dielectric composite that achieves over 16 W m−1 K−1. This breakthrough is enabled by thermal post‐processing, which promotes templated crystallization in a polymer matrix from surface‐modified particles, creating a “hetero‐percolated network.” The resulting material is three ...
Daniel J. Braconnier   +6 more
wiley   +1 more source

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