Results 161 to 170 of about 1,594,713 (267)

Oral Astilbin Nanogels Modulate Senescence‐Associated CD4+ T Cells and Promote Treg Induction in Aged Mice with Colitis

Advanced Science, EarlyView.
Fluorinated β‐glucan/pectin nanogels enable colon‐targeted oral delivery of astilbin through gastrointestinal protection, β‐glucanase‐responsive release, mucus penetration, and prolonged retention. The released astilbin attenuates senescence‐associated features of CD4+ T cells and promotes Treg responses, while the nanogel matrix modulates the gut ...
Lei Zhao, Xinyun Zhang, Qian Ren, Xue Song, Meifang Zhao, Rongshen Wang, Haocheng Du, Yan Chen, Peigen Xu, Jiangyun Liu, Jian Zhang, Jingjing Ma   +11 more
wiley   +1 more source

The nuclear lamina protein NEMP1 regulates tapetal programmed cell death and pollen development in rice. [PDF]

aBIOTECH
Tariq N, Hua M, Li H, Xu Y, Yu F, Rehman A, Li J, Liang W.   +7 more
europepmc   +1 more source

The plant nuclear lamina disassembles to regulate genome folding in stress conditions. [PDF]

Nat Plants, 2023
Wang N, Wang Z, Tzourtzou S, Wang X, Bi X, Leimeister J, Xu L, Sakamoto T, Matsunaga S, Schaller A, Jiang H, Liu C.   +11 more
europepmc   +1 more source

Wafer‐Scale Dendritic Nanoporous Platinum Films for Neural Electrodes

Advanced Science, EarlyView.
Wafer‐scale dendritic nanoporous platinum films with intrinsic nanoscale porosity are synthesized by suraface‐confined wet chemistry and transferred onto flexible substrates to create tissue‐conformal neural electrodes. The ultrathin films combine mechanical flexibility with electrochemical stability, enabling low‐impedance, high‐capacitance interfaces
Kyeongbin Kang, Joosung Oh, Soumen Dutta, Sun Woo Jang, Byeong Su Gu, Woosung Cho, Mingyu Kwak, Sunguk Hong, Seongjae Lee, Hyo Kyoung Jeon, Juwan Han, Keehoon Kim, Sung‐Min Park, Unyong Jeong, In Su Lee   +14 more
wiley   +1 more source

Dysregulated nuclear Lamin B1 in DYT1 dystonia thickens nuclear lamina and disrupts 14-3-3 proteins. [PDF]

Cell Death Discov
Duan Y, Sepehrimanesh M, Hosain MA, Cui H, Stagray J, Shen X, Xiao Y, Li Y, Zhang CL, Ding B.   +9 more
europepmc   +1 more source

Age‐Related Lamin B1 Deficiency Activates SLC7A11‐Dependent Disulfidptosis to Impair Osteogenesis via Intercepting Mitochondrial Fission

Advanced Science, EarlyView.
This study reveals that age‐related LMNB1 deficiency in mesenchymal stem cells epigenetically upregulates SLC7A11, triggering actin disulfidptosis and mitochondrial dysfunction. This cascade impairs bone formation in senile osteoporosis. Furthermore, researchers identified the FDA‐approved drug naldemedine as a targeted SLC7A11 inhibitor to reverse ...
Wenhui Yu, Qibo Li, Weihao Zhang, Guan Zheng, Junhua Chen, Yipeng Zeng, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Jiajie Lin, Zepeng Su, Zhongyu Xie   +12 more
wiley   +1 more source

Interactions between the genome and the nuclear lamina are multivalent and cooperative. [PDF]

Nat Struct Mol Biol
Dauban L, Eder M, de Haas M, Franceschini-Santos VH, Yañez-Cuna JO, Martinovic M, van Schaik T, Leemans C, Teunissen H, Rademaker K, Martinez Ara M, Verkuilen M, de Wit E, van Steensel B.   +13 more
europepmc   +1 more source

Recruitment of a splicing factor to the nuclear lamina for its inactivation. [PDF]

Commun Biol, 2022
Vester K, Preußner M, Holton N, Feng S, Schultz C, Heyd F, Wahl MC.   +6 more
europepmc   +1 more source

Hybrid Spring‐Coupled Broadband Energy Harvester Integrated with CuSCN Functionalized Triboelectric Vibration Sensor for Self‐Sustainable Vehicular IoTs

Advanced Science, EarlyView.
A self‐sustainable vehicular vibration and indoor environment monitoring IoT platform is developed which integrates a hybrid spring‐coupled broadband energy harvester with a machine learning‐assisted PAN‐CuSCN nanofiber triboelectric vibration sensor for subtle‐to‐wide‐range vibration detection and road/speed classification.
Trilochan Bhatta, Gagan Bahadur Pradhan, Shital Sharma, MoonSeong Jo, Aklesh Teli, Hochan Chang, Jae Yeong Park   +6 more
wiley   +1 more source

Nuclear lamina phase separation orchestrates stress-induced transcriptional responses in plants. [PDF]

Dev Cell
Tang Y, Liu X, Fang Y, Calvanese E, Hong Y, Gu Y.   +5 more
europepmc   +1 more source