Results 171 to 180 of about 59,822 (282)

Structurally Complex Precipitates Enhance Strength‐Ductility Synergy in a Duplex Medium Entropy Alloy

Advanced Science, EarlyView.
Strong‐yet‐ductile precipitation‐hardening alloys require novel microstructural complexity of precipitates in particularly at cryogenic condition, to constantly impart strain hardening of hard‐and‐brittle precipitates. The present work creates innovative structurally complex precipitates assembled with dispersed nanocores and a chemical‐heterogeneity ...
Shaohua Gao, Yang Yang, Xiaoxuan Fan, Jinyu Zhang, Shuaiyang Liu, Jiao Li, Hui Wang, Wenli Song, Gang Liu, Jun Sun   +9 more
wiley   +1 more source

Dysregulated nuclear Lamin B1 in DYT1 dystonia thickens nuclear lamina and disrupts 14-3-3 proteins. [PDF]

Cell Death Discov
Duan Y, Sepehrimanesh M, Hosain MA, Cui H, Stagray J, Shen X, Xiao Y, Li Y, Zhang CL, Ding B.   +9 more
europepmc   +1 more source

The Interplay between Oxidative Stress and the Nuclear Lamina Contributes to Laminopathies and Age-Related Diseases. [PDF]

Cells, 2023
Kristiani L, Kim Y.
europepmc   +1 more source

An Energy Autonomous Microneedle Array‐Based Sensing System for Continuous Biomarker Monitoring

Advanced Science, EarlyView.
This work presents an innovative self‐powered wearable biosensor system for real‐time monitoring of multiple biomarkers in interstitial fluid. The device integrates stainless steel‐based minimally invasive microneedles with ion‐selective membranes, enabling simultaneous Na+, K+, Ca2+, pH, and glucose detection.
Arnab Pal, Kai‐Po Fan, Sheng‐Chun Hung, Jaba Roy Chowdhury, Jun‐Hsun Chung, Meenakshi Ray, Hsiang‐Yun Hsu, Fu‐Cheng Kao, Kuei‐Lin Liu, Zong‐Hong Lin   +9 more
wiley   +1 more source

Interactions between the genome and the nuclear lamina are multivalent and cooperative. [PDF]

Nat Struct Mol Biol
Dauban L, Eder M, de Haas M, Franceschini-Santos VH, Yañez-Cuna JO, Martinovic M, van Schaik T, Leemans C, Teunissen H, Rademaker K, Martinez Ara M, Verkuilen M, de Wit E, van Steensel B.   +13 more
europepmc   +1 more source

Recruitment of a splicing factor to the nuclear lamina for its inactivation. [PDF]

Commun Biol, 2022
Vester K, Preußner M, Holton N, Feng S, Schultz C, Heyd F, Wahl MC.   +6 more
europepmc   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

Advanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du, Yinming Li, Ziyue Li, Yuedan Wang, Shaopeng Li, Yijie Wang, Yingying Qu, Bingyang Lv, Ying Li, Ting Chen, Yu Zhou, Xuan Xiao   +11 more
wiley   +1 more source

Nuclear lamina phase separation orchestrates stress-induced transcriptional responses in plants. [PDF]

Dev Cell
Tang Y, Liu X, Fang Y, Calvanese E, Hong Y, Gu Y.   +5 more
europepmc   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

SUV family histone methyltransferases correlate with nuclear lamina remodeling and clinical outcome in cancer: integrative pan-cancer TCGA analysis and experimental evidence. [PDF]

Sci Rep
Kundu S, Akhtar AR, Kumar A, Sharma A.
europepmc   +1 more source