Results 31 to 40 of about 113,787 (272)

Evidence for the existence of Dm0-like Lamin in Sf9 cells

open access: yes浙江大学学报. 农业与生命科学版, 2015
The nuclear membrane of mammalian cells was composed of inner nuclear membrane, outer nuclear membrane and perinuclear space. The lamina was localized under the nucleoplasm face of inner nuclear membrane. It has been known that the lamina was distributed
Wei Wenqiang, Ji Shaoping, Zhang Yinyan
doaj   +1 more source

Mammalian telomeres and their partnership with lamins [PDF]

open access: yes, 2016
Chromosome ends are complex structures, which require a panel of factors for their elongation, replication, and protection. We describe here the mechanics of mammalian telomeres, dynamics and maintainance in relation to lamins.
BURLA, ROMINA   +2 more
core   +1 more source

A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus

open access: yesCell Reports, 2018
Summary: Tcrb locus V(D)J recombination is regulated by positioning at the nuclear periphery. Here, we used DamID to profile Tcrb locus interactions with the nuclear lamina at high resolution.
Shiwei Chen   +7 more
doaj   +1 more source

Autophagy mediates degradation of nuclear lamina [PDF]

open access: yes, 2015
Z.D. is supported by a fellow award from the Leukemia & Lymphoma Society. B.C.C. is supported by career development awards from the Dermatology Foundation, Melanoma Research Foundation, and American Skin Association. S.L.B., P.D.A. and R.M. are supported
A Freund   +37 more
core   +1 more source

Role of lamins in 3D genome organization and global gene expression

open access: yesNucleus, 2019
Genome-wide mapping of lamin-B1-genome interactions has shown that gene-poor and transcriptionally inactive genomic regions are associated with the nuclear lamina.
Youngjo Kim, Xiaobin Zheng, Yixian Zheng
doaj   +1 more source

The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse.

open access: yesPLoS Genetics, 2013
The nuclear lamina is the structural scaffold of the nuclear envelope and is well known for its central role in nuclear organization and maintaining nuclear stability and shape.
Jana Link   +7 more
doaj   +1 more source

Pushing the (nuclear) envelope into meiosis. [PDF]

open access: yes, 2013
A recent study shows that a short isoform of a mammalian nuclear lamin is important for homologous chromosome interactions during meiotic prophase in ...
Dernburg, Abby F
core   +1 more source

Restructuring of Lamina-Associated Domains in Senescence and Cancer

open access: yesCells, 2022
Induction of cellular senescence or cancer is associated with a reshaping of the nuclear envelope and a broad reorganization of heterochromatin. At the periphery of mammalian nuclei, heterochromatin is stabilized at the nuclear lamina via lamina ...
Aurélie Bellanger   +3 more
doaj   +1 more source

The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence [PDF]

open access: yes, 2016
AKTIP is a shelterin-interacting protein required for replication of telomeric DNA. Here, we show that AKTIP biochemically interacts with A- and B-type lamins and affects lamin A, but not lamin C or B, expression.
Astrologo, Letizia   +14 more
core   +2 more sources

The laminA/NF-Y protein complex reveals an unknown transcriptional mechanism on cell proliferation [PDF]

open access: yes, 2016
Lamin A is a component of the nuclear matrix that also controls proliferation by largely unknown mechanisms. NF-Y is a ubiquitous protein involved in cell proliferation composed of three subunits (-YA -YB -YC) all required for the DNA ...
Alonzi, Tonino   +16 more
core   +2 more sources

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