Results 41 to 50 of about 59,822 (282)
Dynamics of subnuclear chromatin organization during "C. elegans" development : a role for H3K9 methylation [PDF]
, 2012 In eukaryotic cells, DNA is packaged into chromatin. This imposes an accessibility barrier to all genetic processes, while at the same time offering the means for tight control.
Towbin, Benjamin Daniel
core +1 more source
The FEBS Journal, 2007 The inner face of the nuclear envelope of metazoan cells is covered by a thin lamina consisting of a one‐layered network of intermediate filaments interconnecting with a complex set of transmembrane proteins and chromatin associating factors. The constituent proteins, the lamins, have recently gained tremendous recognition, because mutations in the ...
Joanna M, Bridger +3 more
openaire +2 more sources
Expression of chicken lamin B2 in Escherichia coli : characterization of its structure, assembly, and molecular interactions [PDF]
, 1991 Chicken lamin B2, a nuclear member of the intermediate-type filament (IF) protein family, was expressed as a full-length protein in Escherichia coli.
Aebi, U. +11 more
core +1 more source
Cells, 2022 Any given cell type has an associated “normal” nuclear morphology, which is important to maintain proper cellular functioning and safeguard genomic integrity.
Anne F. J. Janssen +2 more
doaj +1 more source
PLoS Genetics, 2013 The nuclear lamina is the structural scaffold of the nuclear envelope and is well known for its central role in nuclear organization and maintaining nuclear stability and shape.
Jana Link +7 more
doaj +1 more source
mBio, 2015 We have shown previously that A-type lamins and intranuclear localization of the herpes simplex virus (HSV) genome are critical for the formation of the VP16 activator complex on HSV immediate-early (IE) gene promoters in murine cells, which implies a ...
Hyung Suk Oh +2 more
doaj +1 more source
Restructuring of Lamina-Associated Domains in Senescence and Cancer
Cells, 2022 Induction of cellular senescence or cancer is associated with a reshaping of the nuclear envelope and a broad reorganization of heterochromatin. At the periphery of mammalian nuclei, heterochromatin is stabilized at the nuclear lamina via lamina ...
Aurélie Bellanger +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Lamin B1 mapping reveals the existence of dynamic and functional euchromatin lamin B1 domains
Nature Communications, 2018 Lamina-associated domains (LADs) contact lamins in the nuclear lamina, and lamin B1 was thought to bind heterochromatic regions at the nuclear envelope.
Laura Pascual-Reguant +13 more
doaj +1 more source
Characterization of a Plant Nuclear Matrix Constituent Protein in Liverwort
Frontiers in Plant Science, 2021 The nuclear lamina (NL) is a complex network of nuclear lamins and lamina-associated nuclear membrane proteins, which scaffold the nucleus to maintain structural integrity. In animals, type V intermediate filaments are the main constituents of NL.
Nan Wang +6 more
doaj +1 more source