Results 41 to 50 of about 111,707 (190)

Remodeling of the Nuclear Envelope and Lamina during Bovine Preimplantation Development and Its Functional Implications. [PDF]

open access: yesPLoS ONE, 2015
The present study demonstrates a major remodeling of the nuclear envelope and its underlying lamina during bovine preimplantation development. Up to the onset of major embryonic genome activation (MGA) at the 8-cell stage nuclei showed a non-uniform ...
Jens Popken   +9 more
doaj   +1 more source

Coccinia intermedia [PDF]

open access: yes, 2011
Nuclear and plastid sequences from two individuals of a suspected new species of Coccinia from West Africa were added to an available molecular phylogeny for the remaining 27 species of the genus.
Holstein, Norbert, Renner, Susanne S.
core   +1 more source

Nuclear rupture at sites of high curvature compromises retention of DNA repair factors. [PDF]

open access: yes, 2018
The nucleus is physically linked to the cytoskeleton, adhesions, and extracellular matrix-all of which sustain forces, but their relationships to DNA damage are obscure. We show that nuclear rupture with cytoplasmic mislocalization of multiple DNA repair
Alshareeda   +64 more
core   +2 more sources

Arterial pathology in canine mucopolysaccharidosis-I and response to therapy. [PDF]

open access: yes, 2011
Mucopolysaccharidosis-I (MPS-I) is an inherited deficiency of α-L-iduronidase (IdU) that causes lysosomal accumulation of glycosaminoglycans (GAG) in a variety of parenchymal cell types and connective tissues.
Dickson, Patricia I   +6 more
core   +3 more sources

The nuclear lamina in health and disease [PDF]

open access: yesNucleus, 2016
The nuclear lamina (NL) is a structural component of the nuclear envelope and makes extensive contacts with integral nuclear membrane proteins and chromatin. These interactions are critical for many cellular processes, such as nuclear positioning, perception of mechanical stimuli from the cell surface, nuclear stability, 3-dimensional organization of ...
Dobrzynska, Agnieszka   +3 more
openaire   +5 more sources

Restructuring of Lamina-Associated Domains in Senescence and Cancer

open access: yesCells, 2022
Induction of cellular senescence or cancer is associated with a reshaping of the nuclear envelope and a broad reorganization of heterochromatin. At the periphery of mammalian nuclei, heterochromatin is stabilized at the nuclear lamina via lamina ...
Aurélie Bellanger   +3 more
doaj   +1 more source

A quantitative study of inhibitory interneurons in laminae I-III of the mouse spinal dorsal horn [PDF]

open access: yes, 2013
Laminae I-III of the spinal dorsal horn contain many inhibitory interneurons that use GABA and/or glycine as a neurotransmitter. Distinct neurochemical populations can be recognised among these cells, and these populations are likely to have differing ...
Durrieux, C.   +3 more
core   +2 more sources

The meiotic nuclear lamina regulates chromosome dynamics and promotes efficient homologous recombination in the mouse.

open access: yesPLoS Genetics, 2013
The nuclear lamina is the structural scaffold of the nuclear envelope and is well known for its central role in nuclear organization and maintaining nuclear stability and shape.
Jana Link   +7 more
doaj   +1 more source

Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters

open access: yesmBio, 2015
We have shown previously that A-type lamins and intranuclear localization of the herpes simplex virus (HSV) genome are critical for the formation of the VP16 activator complex on HSV immediate-early (IE) gene promoters in murine cells, which implies a ...
Hyung Suk Oh   +2 more
doaj   +1 more source

Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression [PDF]

open access: yes, 2016
The nuclear lamina is a filamentous structure subtending the nuclear envelope and required for chromatin organization, transcriptional regulation and maintaining nuclear structure.
Alexander V. Ratushny   +14 more
core   +3 more sources

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