Results 41 to 50 of about 1,676,612 (335)

Nuclear lamina component KAKU4 regulates chromatin states and transcriptional regulation in the Arabidopsis genome. [PDF]

BMC Biol
Cao Y, Yan H, Sheng M, Liu Y, Yu X, Li Z, Xu W, Su Z.   +7 more
europepmc   +2 more sources

The Human Protein PRR14 Tethers Heterochromatin to the Nuclear Lamina during Interphase and Mitotic Exit

Cell Reports, 2013
The nuclear lamina is a protein meshwork that lies under the inner nuclear membrane of metazoan cells. One function of the nuclear lamina is to organize heterochromatin at the inner nuclear periphery.
Andrey Poleshko, Katelyn M. Mansfield, Caroline C. Burlingame, Mark D. Andrake, Neil R. Shah, Richard A. Katz   +5 more
doaj   +1 more source

The isolation of the nuclear lamina [PDF]

The Journal of Cell Biology, 2005
The number of monikers early cell biologists attached to the nuclear lamina reflected their uncertainty about its function and architecture, and whether it was widespread or confined to a few specialized cells. Electron micrographs often disclosed a layer of varying thickness nestled against the backside of the nuclear membrane, which various ...
openaire   +2 more sources

Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression [PDF]

, 2016
The nuclear lamina is a filamentous structure subtending the nuclear envelope and required for chromatin organization, transcriptional regulation and maintaining nuclear structure.
Alexander V. Ratushny, Brian T. Chait, David Horn, Hoek, Houben, Jean-Mathieu Bart, John D. Aitchison, Luke Maishman, Marchetti, Mark C. Field, Michael P. Rout, Miguel Navarro, Sam Alsford, Samson O. Obado, Wei-Ming Chen   +14 more
core   +3 more sources

An APEX2 proximity ligation method for mapping interactions with the nuclear lamina

Journal of Cell Biology, 2020
The APEX2 proximity ligation method can identify RNA, protein, and DNA interacting with or in proximity to the nuclear lamina. This work suggests a potential regulation of mRNAs containing long 3′ UTRs and uncovers variation in lamina-associated ...
Joseph R. Tran, Danielle I. Paulson, J. Moresco, S. Adam, J. Yates, R. Goldman, Yixian Zheng   +6 more
semanticscholar   +1 more source

A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence [PDF]

, 2008
The peripheral nuclear lamina, which is largely but not entirely associated with inactive chromatin, is considered to be an important determinant of nuclear structure and gene expression.
Kumaran, R. I., Spector, D. L.
core   +2 more sources

Cyclin D1 integrates G9a-mediated histone methylation. [PDF]

, 2019
Lysine methylation of histones and non-histone substrates by the SET domain containing protein lysine methyltransferase (KMT) G9a/EHMT2 governs transcription contributing to apoptosis, aberrant cell growth, and pluripotency.
Casimiro, Mathew C., Chepelev, Iouri, Dampier, William, Di Sante, Gabriele, Ertel, Adam, Jeltsch, Albert, Jiao, Xuanmao, Ju, Xiaoming, Katiyar, Sanjay, Klopfenstein, D. V., Li, Zhiping, Pestell, Richard G., Tozeren, Aydin, Wang, Min   +13 more
core   +2 more sources

Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes.

, 2020
The nucleus of oocytes (germinal vesicle) is unusually large and its nuclear envelope (NE) is densely packed with nuclear pore complexes (NPCs) stockpiled for embryonic development. We showed that breakdown of this specialized NE is mediated by an Arp2/3-
Avilov, I., Geiss, C., Kondo, H., Lenart, P., Machado, P., Mori, M., Wesolowska, N.   +6 more
core   +1 more source

The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation

bioRxiv, 2020
Cell fate decisions are essential for tissue development and homeostasis and can be induced by chemical and mechanical inputs. While the mechanisms by which chemical signals control cell fate have been well studied, how mechanical inputs impact cell fate
E. Carley, Rachel Stewart, A. Zieman, A. Zubek, Samantha Lin, V. Horsley, M. King   +6 more
semanticscholar   +1 more source

Alterations to nuclear architecture and genome behavior in senescent cells. [PDF]

, 2007
The organization of the genome within interphase nuclei, and how it interacts with nuclear structures is important for the regulation of nuclear functions.
Abney J.R., Agrelo R., Barboro P., Becker P.B., Bemiller P.M., Benn P.A., Berezney R., Bowman P.D., Bridger J.M., Bridger J.M., C. S. CLEMENTS, Campisi J., Chaly N., Chang K.S., Cremer T., de Lange T., Dell'Orco R.T., Dijkwel P.A., Ferbeyre G., Filesi I., Fisher A.G., Fleischer S., Goldman R.D., Gruenbaum Y., Haque F., Hernandez-Verdun D., Holliday R., Hozak P., I. R. KILL, I. S. MEHTA, J. M. BRIDGER, Kill I.R., Kreth G., Lezhava T., Li Y., M. FIGGITT, Mallette F.A., Manuelidis L., Mazin A.L., Mitsui Y., Mukherjee A.B., Nickerson J., Okabe J., Padiath Q.S., Pawelec G., Petrova N.V., Schardin M., Schulz L., Smilenov L.B., Strouboulis J., Tanabe H., van Driel R., Wang G.S.   +52 more
core   +1 more source