Results 51 to 60 of about 929,541 (348)
Specific nuclear localizing sequence directs two myosin isoforms to the cell nucleus in calmodulin-sensitive manner. [PDF]
PLoS ONE, 2012 BACKGROUND: Nuclear myosin I (NM1) was the first molecular motor identified in the cell nucleus. Together with nuclear actin, they participate in crucial nuclear events such as transcription, chromatin movements, and chromatin remodeling.
Rastislav Dzijak +6 more
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Nuclear dynamics: Formation of bodies and trafficking in plant nuclei
Frontiers in Plant Science, 2022 The existence of the nucleus distinguishes prokaryotes and eukaryotes. Apart from containing most of the genetic material, the nucleus possesses several nuclear bodies composed of protein and RNA molecules.
Eduardo Muñoz-Díaz +3 more
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Frontiers in Plant Science, 2014 Recent ultrastructural studies revealed that a structure similar to the vertebrate nuclear lamina exists in the nuclei of higher plants. However, plant genomes lack genes for lamins and intermediate-type filament proteins, and this suggests that plant ...
Yuta eKimura +3 more
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Human Gene Therapy, 1999 Polylysine (pLy) has been used successfully as a DNA carrier in receptor-mediated gene transfer, enhancement of transfection having been proposed to be in part through efficient nuclear targeting stemming from the resemblance of pLy to the nuclear localization sequence (NLS) from simian virus SV40 large tumor antigen (T-ag).
Chan, Chee Kai, Jans, David A
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Viruses, 2023 Replication of the RNA genome of influenza A virus occurs in the nucleus of infected cells. The influenza nucleoprotein (NP) associated with the viral RNA into ribonucleoprotein complexes (vRNPs) is involved in the nuclear import of the viral genome.
Nhan L. T. Nguyen, Wei Wu, Nelly Panté
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Identification of a Bipartite Nuclear Localization Sequence Necessary for Nuclear Import of 5-Lipoxygenase [PDF]
Journal of Biological Chemistry, 1999 5-Lipoxygenase catalyzes the synthesis of leukotrienes from arachidonic acid. This enzyme can reside either in the cytoplasm or the nucleus; its subcellular distribution is influenced by extracellular factors, and its nuclear import correlates with changes in leukotriene synthetic capacity.
Ji Ping Yao +3 more
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Diffusion of Proteins Across the Nuclear Envelope of HeLa Cells
BioTechniques, 1998 We describe an experimental system to study nucleocytoplasmic diffusion of proteins in living HeLa cells. To localize proteins to the nucleus, substrates were created that contain a nuclear localization sequence fused to Aequorea victoria green ...
Shivani Chatterjee, Ursula Stochaj
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The Nuclear Localization of Glycogen Synthase Kinase 3β Is Required Its Putative PY-Nuclear Localization Sequences [PDF]
Molecules and Cells, 2012 Glycogen synthase kinase-3β(GSK-3β), which is a member of the serine/threonine kinase family, has been shown to be crucial for cellular survival, differentiation, and metabolism. Here, we present evidence that GSK-3β is associated with the karyopherin β2 (Kap β2) (102-kDa), which functions as a substrate for transportation into the nucleus. A potential
Sunghee Hyun +5 more
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The Ebola Virus Interferon Antagonist VP24 Undergoes Active Nucleocytoplasmic Trafficking
Viruses, 2021 Viral interferon (IFN) antagonist proteins mediate evasion of IFN-mediated innate immunity and are often multifunctional, with distinct roles in viral replication.
Angela R. Harrison +3 more
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Nuclear Targeting of the Maize R Protein Requires Two Nuclear Localization Sequences [PDF]
Plant Physiology, 1993 Previous genetic and structural evidence indicates that the maize R gene encodes a nuclear transcriptional activating factor. In-frame carboxyl- and amino-terminal fusions of the R gene to the reporter gene encoding beta-glucuronidase (GUS) were sufficient to direct GUS to the nucleus of the transiently transformed onion (Allium cepa) epidermal cells ...
Susan R. Wessler +2 more
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