Results 41 to 50 of about 292,166 (318)

IPSE, a parasite-derived, host immunomodulatory infiltrin protein, alleviates resiniferatoxin-induced bladder pain

Molecular Pain, 2020
The transient receptor potential cation channel subfamily V member 1 (TRPV1) receptor is an important mediator of nociception and its expression is enriched in nociceptive neurons.
Kenji Ishida, Evaristus C Mbanefo, Loc Le, Olivia Lamanna, Luke F Pennington, Julia C Finkel, Theodore S Jardetzky, Franco H Falcone, Michael H Hsieh   +8 more
doaj   +1 more source

Effect of Different Nuclear Localization Signals on the Subcellular Localization and Anti-HIV-1 Function of the MxB Protein

Frontiers in Microbiology, 2021
Interferon exerts its antiviral activity by stimulating the expression of antiviral proteins. These interferon stimulate genes (ISGs) often target a group of viruses with unique molecular mechanisms.
Keli Chai, Keli Chai, Keli Chai, Zhen Wang, Zhen Wang, Qinghua Pan, Juan Tan, Wentao Qiao, Chen Liang, Chen Liang, Chen Liang   +10 more
doaj   +1 more source

A nuclear targeting system in Plasmodium falciparum

Malaria Journal, 2010
Background The distinct differences in gene control mechanisms acting in the nucleus between Plasmodium falciparum and the human host could lead to new potential drug targets for anti-malarial development.
Kochakarn Theerarat, Songprakhon Pucharee, Tinikul Ruchanok, Kumpornsin Krittikorn, Uthaipibull Chairat, Wittayacom Kanjana, Chookajorn Thanat   +6 more
doaj   +1 more source

Correction for Miao et al., Severe growth retardation and early lethality in mice lacking the nuclear localization sequence and C-terminus of PTH-related protein. [PDF]

Proc Natl Acad Sci U S A
europepmc   +3 more sources

The molecular mechanism underlying the differential subcellular distribution of dystrophin Dp71 isoforms. [PDF]

Cell Biosci
Background Dystrophin Dp71 is a versatile protein that plays a critical role in regulating diverse processes, including cell adhesion, nuclear architecture, neuronal differentiation, and synapse organization.
Alamillo-Iniesta A, Velez-Aguilera G, Monterrubio-Ledezma F, Ávila-Avilés RD, Suárez-Sánchez R, García-Aguirre I, Lizcano-Meneses S, López-Orona TI, Guevara-Namorado F, Toribio-Valdez A, Hernández-Hernández JM, Arrieta-Cruz I, Magaña JJ, Cisneros B.   +13 more
europepmc   +2 more sources

Identification of a Bipartite Nuclear Localization Sequence Necessary for Nuclear Import of 5-Lipoxygenase [PDF]

Journal of Biological Chemistry, 1999
5-Lipoxygenase catalyzes the synthesis of leukotrienes from arachidonic acid. This enzyme can reside either in the cytoplasm or the nucleus; its subcellular distribution is influenced by extracellular factors, and its nuclear import correlates with changes in leukotriene synthetic capacity.
A M, Healy, M, Peters-Golden, J P, Yao, T G, Brock   +3 more
openaire   +2 more sources

RAM function is dependent on Kapβ2-mediated nuclear entry [PDF]

, 2014
Eukaryotic gene expression is dependent on the modification of the first transcribed nucleotide of pre-mRNA by the addition of the 7-methylguanosine cap.
Gonatopoulos-Pournatzis, Thomas, Cowling, Victoria H   +1 more
core   +1 more source

Specific nuclear localizing sequence directs two myosin isoforms to the cell nucleus in calmodulin-sensitive manner. [PDF]

PLoS ONE, 2012
BACKGROUND: Nuclear myosin I (NM1) was the first molecular motor identified in the cell nucleus. Together with nuclear actin, they participate in crucial nuclear events such as transcription, chromatin movements, and chromatin remodeling.
Rastislav Dzijak, Sukriye Yildirim, Michal Kahle, Petr Novák, Jarmila Hnilicová, Tomáš Venit, Pavel Hozák   +6 more
doaj   +1 more source

Nuclear Effectors in Plant Pathogenic Fungi

Mycobiology, 2022
The nuclear import of proteins is a fundamental process in the eukaryotes including plant. It has become evident that such basic process is exploited by nuclear effectors that contain nuclear localization signal (NLS) and are secreted into host cells by ...
Surajit De Mandal, Junhyun Jeon
doaj   +1 more source

Nuclear dynamics: Formation of bodies and trafficking in plant nuclei

Frontiers in Plant Science, 2022
The existence of the nucleus distinguishes prokaryotes and eukaryotes. Apart from containing most of the genetic material, the nucleus possesses several nuclear bodies composed of protein and RNA molecules.
Eduardo Muñoz-Díaz, Eduardo Muñoz-Díaz, Julio Sáez-Vásquez, Julio Sáez-Vásquez   +3 more
doaj   +1 more source