Results 31 to 40 of about 8,215,941 (358)

Endogenous hydrogen sulfide inhibition suppresses tumor growth by promoting apoptosis and pyroptosis in esophageal cancer cells

open access: yesTranslational Oncology, 2023
Background: Hydrogen sulfide (H2S) has been identified as the third gaseous signaling molecule. Endogenous H2S plays a key role in the progression of various types of cancer.
Hong-Gang Wang   +13 more
doaj   +1 more source

The Application of Nanotechnology for the Diagnosis and Treatment of Brain Diseases and Disorders

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Brain is by far the most complex organ in the body. It is involved in the regulation of cognitive, behavioral, and emotional activities. The organ is also a target for many diseases and disorders ranging from injuries to cancers and neurodegenerative ...
Ebenezeri Erasto Ngowi   +19 more
doaj   +1 more source

Taking a holistic view of PEST‐containing nuclear protein (PCNP) in cancer biology

open access: yesCancer Medicine, 2019
Polypeptide sequences enriched with proline (P), glutamic acid (E), aspartic acid (D) and serine (S)/ threonine (T) (PEST) have been reported to be the most abundant and frequently distributed at the cellular level.
Attia Afzal   +7 more
doaj   +1 more source

Nuclear Polyadenylate-Binding Protein [PDF]

open access: yesMolecular and Cellular Biology, 1985
Polyadenylate-binding activity can be detected in eluates from sodium dodecyl sulfate gels by a nitrocellulose filter-binding assay. Nuclear extracts from rat liver show a single peak of binding activity at 50 to 55 kilodaltons; cytoplasmic extracts show a single peak at 70 to 80 kilodaltons, corresponding to a 75-kilodalton protein previously ...
A B, Sachs, R D, Kornberg
openaire   +2 more sources

Progress in Research on SARS-CoV-2 Infection Causing Neurological Diseases and Its Infection Mechanism

open access: yesFrontiers in Neurology, 2021
COVID-19 has spread rapidly worldwide since its outbreak and has now become a major public health problem. More and more evidence indicates that SARS-CoV-2 may not only affect the respiratory system but also cause great harm to the central nervous system.
Lintao Wang   +12 more
doaj   +1 more source

Biology of PEST‐Containing Nuclear Protein: A Potential Molecular Target for Cancer Research

open access: yesFrontiers in Oncology, 2022
PEST-containing nuclear protein (PCNP), a novel nuclear protein, is involved in vital cellular processes like cell proliferation and mediates tumorigenesis.
Nazeer Hussain Khan   +14 more
doaj   +1 more source

Insight into the Double-Edged Role of Ferroptosis in Disease

open access: yesBiomolecules, 2021
Ferroptosis, a newly described type of iron-dependent programmed cell death that is distinct from apoptosis, necroptosis, and other types of cell death, is involved in lipid peroxidation (LP), reactive oxygen species (ROS) production, and mitochondrial ...
Lei Zhang   +7 more
doaj   +1 more source

Successful Recovery of Nuclear Protein-Coding Genes from Small Insects in Museums Using Illumina Sequencing

open access: yesPLoS ONE, 2015
In this paper we explore high-throughput Illumina sequencing of nuclear protein-coding, ribosomal, and mitochondrial genes in small, dried insects stored in natural history collections.
K. Kanda   +4 more
semanticscholar   +1 more source

Hydrogen Sulfide Biology and Its Role in Cancer

open access: yesMolecules, 2022
Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian tissues. It plays a very critical role in many pathophysiological processes in the body.
Saadullah Khattak   +11 more
doaj   +1 more source

Nuclear constriction segregates mobile nuclear proteins away from chromatin [PDF]

open access: yesMolecular Biology of the Cell, 2016
As a cell squeezes its nucleus through adjacent tissue, penetrates a basement membrane, or enters a small blood capillary, chromatin density and nuclear factors could in principle be physically perturbed. Here, in cancer cell migration through rigid micropores and in passive pulling into micropipettes, local compaction of chromatin is observed ...
Irianto, Jerome   +7 more
openaire   +2 more sources

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