Results 81 to 90 of about 1,042,939 (323)
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
HEPATITIS C VIRUS AND HOST CELL NUCLEAR TRANSPORT MACHINERY: A CLANDESTINE AFFAIR
Frontiers in Microbiology, 2015 There is growing evidence that factors encoded by cytoplasmic replicating viruses functionally interact with components of the nucleocytoplasmic transport apparatus.
Barbara eBonamassa +5 more
doaj +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Comment on "Exactly central heavy-ion collisions by nuclear hydrodynamics" [PDF]
, 2006 Problems arising in viscous nuclear fluid dynamical models of high-energy heavy-ion collisions are discussed. The importance of an accurate treatment of the transport properties of the hot and dense nuclear matter is pointed ...
Csernai, László Pal, Stöcker, Horst
core
Effects of momentum-dependent nuclear potential on two-nucleon correlation functions and light cluster production in intermediate energy heavy-ion collisions [PDF]
, 2004 Using an isospin- and momentum-dependent transport model, we study the effects due to the momentum dependence of isoscalar nuclear potential as well as that of symmetry potential on two-nucleon correlation functions and light cluster production in ...
B. A. Li +3 more
core +2 more sources
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design
FEBS Letters, EarlyView.Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos +3 more
wiley +1 more source
, 2004 Using an isospin- and momentum-dependent transport model we study the emission of free nucleons and the nuclear radial flow in central heavy-ion collisions induced by high energy radioactive beams.
B. A. Li +3 more
core +1 more source
Heavy quarks and charmonium at RHIC and LHC within a partonic transport model [PDF]
, 2011 Heavy quark and charmonium production as well as their space-time evolution are studied in transport simulations of heavy-ion collisions at RHIC and LHC.
Fochler, Oliver +4 more
core +2 more sources
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source