Results 131 to 140 of about 323,426 (336)
Advanced Science, EarlyView.A rapidly fabricated hydrogel‐SiO2 composite enables ultralow‐cost, equipment‐minimized DNA extraction, outperforming commercial kits. Hierarchical microstructures enhance hydrophobic/salt‐bridge‐driven adsorption. Integrated with visual LAMP, this field‐deployable system detects Vibrio parahaemolyticus at 10 CFU mL−1 in <40 min, offering ...
Peipei Li +9 more
wiley +1 more source
High throughput oscillating-flow structure for polymerase chain reaction
AIP AdvancesPolymerase chain reaction (PCR) is a revolutionary biomolecule technology that drives the development of bioscience. The current work reports a high throughput oscillating-flow PCR structure.
Ranran Zhou +7 more
doaj +1 more source
A Charge‐Adhesive Targeted DNA Gel Bandage for the Precision Treatment of Inflammatory Bowel Disease
Advanced Science, EarlyView.DNA gel bandage (DNAgb) is designed to precisely target the site of inflammation of IBD, by achieving dual specific localization of inflamed mucosa through electrostatic interactions and ApITGA4‐mediated affinity targeting. DNAgb effectively the activation of inflammatory pathways and reshapes the immune microenvironment.
Peifen Lu +9 more
wiley +1 more source
Advanced Science, EarlyView.This review summarizes recent advances in cGAS‐STING agonist‐based nanotherapeutics for cancer combination therapy. It explores nanoparticle‐mediated delivery strategies, underlying molecular mechanisms, and combinatorial applications with chemotherapy, radiotherapy, targeted therapy, phototherapy, sonodynamic therapy, and immunotherapy.
Zhaomeng Wang +3 more
wiley +1 more source
Next NanotechnologyNanotechnology has revolutionized biomedical sciences, with silver nanoparticles (AgNPs) gaining attention for their antimicrobial, antioxidant, and anti-inflammatory properties. However, conventional synthesis methods often involve toxic chemicals.
Sapam Riches Singh +9 more
doaj +1 more source
Aggregate, EarlyView.TPAOMCN exhibits optimal reactive oxygen species (ROS) generation and photothermal conversion properties. TPAOMCN nanofibers (NFs)‐mediated photodynamic (PDT) and photothermal therapy (PTT) achieved efficient eradication against multidrug‐resistant bacteria and viruses, alleviating inflammation response, promoting wound healing, and providing a ...
Laiping Fang +9 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai +8 more
wiley +1 more source
Advances on Albumin‐Based Carriers for Anticancer Drug Delivery
Advanced NanoBiomed Research, EarlyView.This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou +4 more
wiley +1 more source
Antibacterial hydrogel: The sniper of chronic wounds
BMEMat, EarlyView.The treatment of chronic wounds has always been an important challenge in the medical field. We focus on hydrogels not only because they provide a moist healing environment but also because compared with traditional dressings, they can effectively prevent and treat infections, reduce wound pain and scar formation.
Shengtai Bian +6 more
wiley +1 more source
Polymerase-endonuclease amplification reaction for large-scale enzymatic production of antisense oligonucleotide [PDF]
, 2009 Synthetic oligonucleotides are contaminated with highly homologous failure sequences. Oligonucleotide synthesis is difficult to scale up because it requires expensive equipments, hazardous chemicals, and tedious purification process.
Deming Gou, Xiaolong Wang
core +1 more source