Investigation of the Characteristics of NLS-PNA: Influence of NLS Location on Invasion Efficiency
Peptide nucleic acid can recognise sequences in double-stranded DNA (dsDNA) through the formation of a double-duplex invasion complex. This double-duplex invasion is a promising method for the recognition of dsDNA in cellula because peptide nucleic acid (
Yuichiro Aiba+3 more
doaj +1 more source
Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation. [PDF]
At autopsy, the time that has elapsed since the time of death is routinely documented and noted as the postmortem interval (PMI). The PMI of human tissue samples is a parameter often reported in research studies and comparable PMI is preferred when ...
Jeffrey A Blair+11 more
doaj +1 more source
Single-cell analysis reveals microbial spore responses to microwave radiation
To determine the effects of microwave radiation at the molecular level as well as on the germination, growth and morphology of dry spores at the single-cell level.
Siyi Qiu, Haihua Fan, Lin He
doaj +1 more source
Physiological and biochemical responses of Yarrowia lipolytica to dehydration induced by air-drying and freezing. [PDF]
Organisms that can withstand anhydrobiosis possess the unique ability to temporarily and reversibly suspend their metabolism for the periods when they live in a dehydrated state.
Caroline Pénicaud+6 more
doaj +1 more source
Fabrication of Silver Nanoparticles Against Fungal Pathogens
The use of silver nanoparticles (AgNPs) against various pathogens is now being well recognized in the agriculture and health sector. Nanoparticles have been shown to exhibit various novel properties and these properties, on other hand, rely upon the size,
Sheikh Mansoor+6 more
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Probing structural heterogeneities and fluctuations of nucleic acids and denatured proteins [PDF]
We study protein and nucleic acid structure and dynamics using single-molecule FRET and alternating-laser excitation. Freely diffusing molecules are sorted into subpopulations based on single-molecule signals detected within 100 μs to 1 ms.
Laurence, T A+3 more
openaire +4 more sources
Atomic scissors: a new method of tracking the 5-bromo-2'-deoxyuridine-labeled DNA in situ. [PDF]
A new method of the light microscopy detection of BrdU-labeled DNA in situ is described. It is based on the oxidative attack at the deoxyribose moiety by copper(I) in the presence of oxygen, which leads to the abstraction of hydrogen atom from ...
Anna Ligasová+4 more
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Base composition of DNA in adenovirus-12-induced tumor [PDF]
A series of experiments was conducted to study the base composition of DNA in AVl2-induced tumor and host cells by paper chromatography, and it was found that DNA per cent. guanine-cystosine contents were around 42 % in both of them. The base composition
Ohmori, Masaki
core +1 more source
Polymerase chain reaction (PCR) is a revolutionary innovation involving enzymatic amplification of nucleic acid sequences in repeated cycles of denaturation, oligonucleotide annealing, and DNA polymerase extension.
Arkaprava Pradhan+2 more
doaj +1 more source
Observation of coherent delocalized phonon-like modes in DNA under physiological conditions [PDF]
Underdamped terahertz-frequency delocalized phonon-like modes have long been suggested to play a role in the biological function of DNA. Such phonon modes involve the collective motion of many atoms and are prerequisite to understanding the molecular ...
Ellis, Elizabeth M.+6 more
core +1 more source