Results 21 to 30 of about 252,695 (308)

Computer programs to assist in high resolution thermal denaturation and circular dichroism studies on nucleic acids [PDF]

Nucleic Acids Research, 1981
Computer programs are described that direct the collection, processing, and graphical display of numerical data obtained from high resolution thermal denaturation (1-3) and circular dichroism (4) studies. Besides these specific applications, the programs may also be useful, either directly or as programming models, in other types of spectrophotometric ...
Thomas C. Goodman, Stephen C. Hardies, Carlos Rodrigo Cortez, Wolfgang Hillen   +3 more
openalex   +4 more sources

Nucleic acid binding and other biomedical properties of artificial oligolysines

International Journal of Nanomedicine, 2016
Giovanni N Roviello,1 Caterina Vicidomini,1 Vincenzo Costanzo,1 Valentina Roviello2 1CNR Istituto di Biostrutture e Bioimmagini, Via Mezzocannone site and Headquarters, 2Centro Regionale di Competenza (CRdC) Tecnologie, Via Nuova Agnano, Napoli, Italy ...
Roviello GN, Vicidomini C, Costanzo V, Roviello V   +3 more
doaj   +2 more sources

Partial Denaturation of Double-Stranded DNA on Pristine Graphene under Physiological-like Conditions

Liquids, 2023
Interactions between DNA and graphene are paramount for a wide range of applications, such as biosensing and nanoelectronics; nonetheless, the molecular details of such interactions remain largely unexplored.
Fernando J. A. L. Cruz, José P. B. Mota
doaj   +2 more sources

Electrostatic surface plasmon resonance: Direct electric field-induced hybridization and denaturation in monolayer nucleic acid films and label-free discrimination of base mismatches

Proceedings of the National Academy of Sciences of the United States of America, 2001
Richard J. Heaton, Alexander W. Peterson, R. Georgiadis   +2 more
openalex   +3 more sources

Development and performance evaluation of a streamlined method for nucleic acid purification, denaturation, and multiplex detection of Bluetongue virus and Epizootic hemorrhagic disease virus

Journal of Veterinary Diagnostic Investigation, 2013
Megan E. Schroeder, Donna J. Johnson, Eileen N. Ostlund, Jennifer Meier, Mangkey A. Bounpheng, Alfonso Clavijo   +5 more
openalex   +2 more sources

Fast and non-toxic in situ hybridization without blocking of repetitive sequences. [PDF]

PLoS ONE, 2012
Formamide is the preferred solvent to lower the melting point and annealing temperature of nucleic acid strands in in situ hybridization (ISH). A key benefit of formamide is better preservation of morphology due to a lower incubation temperature. However,
Steen H Matthiesen, Charles M Hansen
doaj   +1 more source

Ultrafast Microfluidic PCR Thermocycler for Nucleic Acid Amplification

Micromachines, 2023
The polymerase chain reaction (PCR) is essential in nucleic acid amplification tests and is widely used in many applications such as infectious disease detection, tumor screening, and food safety testing; however, most PCR devices have inefficient ...
Yi-Quan An, Shao-Lei Huang, Bang-Chao Xi, Xiang-Lian Gong, Jun-Hao Ji, You Hu, Yi-Jie Ding, Dong-Xu Zhang, Sheng-Xiang Ge, Jun Zhang, Ning-Shao Xia   +10 more
doaj   +1 more source

Single-tube collection and nucleic acid analysis of clinical samples for SARS-CoV-2 saliva testing

Scientific Reports, 2022
The SARS-CoV-2 pandemic has brought to light the need for expedient diagnostic testing. Cost and availability of large-scale testing capacity has led to a lag in turnaround time and hindered contact tracing efforts, resulting in a further spread of SARS ...
K. Cole, A. Bouin, Caila Ruiz, B. Semler, M. Inlay, A. Lupták   +5 more
semanticscholar   +1 more source

Regulatory effect of apoptosis on morphological changes in cell mass of porcine blastocyst through supplementation of rapamycin during in vitro culture

Journal of Advanced Veterinary and Animal Research, 2020
Objective: The study of an in vitro embryosis is crucial in genetics for breed improvement and reproduction in livestock, identifying the causes of infertility, and stem cell application.
Dae Seung Kim, Sang Hwan Kim, Jong Taek Yoon   +2 more
doaj   +1 more source

Investigation of the Characteristics of NLS-PNA: Influence of NLS Location on Invasion Efficiency

Applied Sciences, 2020
Peptide nucleic acid can recognise sequences in double-stranded DNA (dsDNA) through the formation of a double-duplex invasion complex. This double-duplex invasion is a promising method for the recognition of dsDNA in cellula because peptide nucleic acid (
Yuichiro Aiba, Gerardo Urbina, Masanari Shibata, Osami Shoji   +3 more
doaj   +1 more source