Results 31 to 40 of about 4,329 (140)

Actinopolyspora algeriensis sp. nov., a novel halophilic actinomycete isolated from a Saharan soil [PDF]

, 2012
A halophilic actinomycete strain designated H19T, was isolated from a Saharan soil in the Bamendil region (Ouargla province, South Algeria) and was characterized taxonomically by using a polyphasic approach.
Klenk, Hans-Peter, Meklat, Atika, Schumann, Peter, Sabaou, Nasserdine, Bouras, Noureddine, Zitouni, Abdelghani, Mathieu, Florence, Lebrihi, Ahmed, Spröer, Cathrin   +8 more
core   +1 more source

Emerging Biomimetic Drug Delivery Nanoparticles Inspired by Extracellular Vesicles

WIREs Nanomedicine and Nanobiotechnology, Volume 17, Issue 4, July/August 2025.
An overview of various nanoparticles reviewed in this article and their mechanism of cellular targeting. ABSTRACT Nanoparticles (NPs) made up of cellular components such as extracellular vesicles (EVs) with a biomimetic outlook have emerged as a revolutionary approach in nanomedicine, providing significant benefits for targeted drug administration ...
Viswanathan Sundaram, Santosh Aryal
wiley   +1 more source

Two-dimensional strandness-dependent electrophoresis: a method to characterize single-stranded DNA, double-stranded DNA, and RNA-DNA hybrids in complex samples

, 2007
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldWe describe two-dimensional strandness-dependent electrophoresis (2D-SDE) for quantification and length distribution analysis of single-stranded
Gunnarsson, Gudmundur H, Gudmundsson, Bjarki, Thormar, Hans G, Alfredsson, Arni, Jonsson, Jon J   +4 more
core   +1 more source

Studies on nucleic acid reassociation kinetics: V. Effects of disparity in tracer and driver fragment lengths [PDF]

, 1978
Measurements are described of the kinetics of nucleic acid strand pair reassoci ation where the complementary strands are of different lengths and are present in different concentrations.
Chamberlin, Margaret E., Davidson, Eric H., Galau, Glenn A., Britten, Roy J.   +3 more
core  

Anti‐Prion Systems in Saccharomyces cerevisiae

Journal of Neurochemistry, Volume 169, Issue 3, March 2025.
Yeast pathogenic prions have the same in‐register parallel folded β‐sheet architecture as infectious amyloids of human transmissible spongiform encephalopathy, Alzheimer's disease, Parkinson's disease, and type 2 diabetes. Six anti‐prion systems in yeast (identified by their gene names) together lower the load of prions detected ~5000‐fold by blocking ...
Reed B. Wickner, Yuho Hayashi, Herman K. Edskes   +2 more
wiley   +1 more source

Visualization of the hepatic and renal cell uptake and trafficking of tetrahedral DNA origami in tumour

Cell Proliferation, Volume 57, Issue 8, August 2024.
After intravenous injection in mice, tetrahedral DNA origami (TDOs) accumulate in renal tubules and are metabolized by Kupffer cells, epithelial cells, and hepatocytes in the liver. In a tumour‐bearing mouse model, TDOs passively target tumour tissues and exhibit excellent tumour penetration and retention after rapid metabolism in hepatocytes ...
Shitai Zhu, Hongzhen Peng, Huating Kong, Qinglong Yan, Kai Xia, Lihua Wang, Ying Zhu, Shihua Luo   +7 more
wiley   +1 more source

Homopolymeric pyrrolidine-amide oligonucleotide mimics: Fmoc-synthesis and DNA/RNA binding properties

, 2007
By chemically modifying or replacing the backbone of oligonucleotides it is possible to modulate the DNA and RNA recognition properties and fine-tune the physiochemical properties of oligomers. This is important because it challenges our understanding of
Worthington, Roberta J., Tan, T. H. Samuel, Morral-Cardoner, Jordi, Micklefield, Jason, Pritchard, Robin G., Morral, Jordi, Tan, T. H Samuel   +6 more
core   +1 more source

GpEF1A: a novel lysine methyltransferase gene from Gypsophila perfoliata L. involved in boron homeostasis

Plant Biology, Volume 26, Issue 5, Page 727-734, August 2024.
Yeast functional screening identified GpEF1A from Gypsophila perfoliata potentially to be utilized to generate B stress‐tolerant plants. Abstract Rapid accumulation of boron (B) leads to toxicity in plant tissues, and the narrow gap between deficiency and toxicity makes it difficult to adjust essential B levels in soil for plant productivity. Therefore,
M. A. Akbudak, N. Cirik, S. N. Erdeger, E. Filiz, S. Dogu, M. Bor   +5 more
wiley   +1 more source

Measurement of Telomere Length Using PNA Probe by Cytometry

, 2011
Peptide nucleic acid (PNA) probes hybridize to denatured telomeric sequences in cells permeabilized in hot formamide. In reported protocols, the hybridization was conducted in solutions with high formamide concentrations to avoid the DNA renaturation ...
CARBONARI, Maurizio, Maurizio Carbonari, Angela Catizone, Marina Cibati, CATIZONE, Angiolina, FIORILLI, Massimo, Massimo Fiorilli, Nicla Sette   +7 more
core   +1 more source

Determinants in the phage life cycle: The dynamic nature of ssDNA phage FLiP and host interactions under varying environmental conditions and growth phases

Environmental Microbiology, Volume 26, Issue 7, July 2024.
The interactions between the lipid‐containing ssDNA phage FLiP and its three Flavobacterium hosts are influenced by factors such as the host strain and culture conditions, including temperature and bacterial growth phase. Abstract The influence of environmental factors on the interactions between phages and bacteria, particularly single‐stranded DNA ...
Kati Mäkelä, Elina Laanto, Lotta‐Riina Sundberg   +2 more
wiley   +1 more source