Results 211 to 220 of about 2,216,606 (233)
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Structural Biology of Nucleocytoplasmic Transport
Annual Review of Biochemistry, 2007In eukaryotic cells, segregation of DNA replication and RNA biogenesis in the nucleus and protein synthesis in the cytoplasm poses the requirement of transporting thousands of macromolecules between the two cellular compartments. Transport between nucleus and cytoplasm is mediated by soluble receptors that recognize specific cargoes and carry them ...
Cook, A., Bono, F., Jinek, M., Conti, E.
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SUMO and Nucleocytoplasmic Transport
2009The transport of proteins between the nucleus and cytoplasm occurs through nuclear pore complexes and is facilitated by numerous transport factors. These transport processes are often regulated by post-translational modification or, reciprocally, transport can function to control post-translational modifications through regulated transport of key ...
Christopher, Ptak, Richard W, Wozniak
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Karyopherin flexibility in nucleocytoplasmic transport
Current Opinion in Structural Biology, 2006Recent structural work on nuclear transport factors of the importin-beta superfamily of karyopherins has shown that these proteins are superhelices of HEAT repeats that are able to assume different conformations in different functional states. The inherent flexibility of these helicoids facilitates the accommodation of different binding partners by an ...
Elena, Conti +2 more
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Control of nucleocytoplasmic transport
Current Opinion in Cell Biology, 1992The movement of macromolecules between the nucleus and cytoplasm is tightly controlled. In the past few years it has become increasingly apparent that nuclear traffic is regulated not only by recognition of specific signals on proteins and RNAs, but also by cellular factors that modulate the efficacy with which these signals are recognized.
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Nucleocytoplasmic RNA Transport
1984During the past decade, it has become evident that, in eukaryotes, RNA molecules undergo a complex series of chemical modifications after transcription and before translation and that some of these modifications coincide with alterations in subcellular distribution.
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Regulated nucleocytoplasmic transport during gametogenesis
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2012Gametogenesis is the process by which sperm or ova are produced in the gonads. It is governed by a tightly controlled series of gene expression events, with some common and others distinct for males and females. Nucleocytoplasmic transport is of central importance to the fidelity of gene regulation that is required to achieve the precisely regulated ...
Yoichi, Miyamoto +3 more
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Nuclear envelope dynamics and nucleocytoplasmic transport
Journal of Cell Science, 1991ABSTRACT We have combined structural, biochemical and recombinant DNA methods to explore molecular interactions involved in nuclear envelope assembly dynamics and nucleocytoplasmic transport. Electron microscopy has established the overall architecture of the envelope and the relationship between nuclear pores, lamina fibres and pore ...
M, Stewart, S, Whytock, R D, Moir
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Intracellular Structure and Nucleocytoplasmic Transport
1996Intracellular movement of any solute or particle accords with one of two general schemes: either it takes place predominantly in the solution phase or it occurs by dynamic interactions with solid-state structures. If nucleocytoplasmic exchanges of macromolecules and complexes are predominantly solution-phase processes, i.e., if the former ...
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