Results 131 to 140 of about 19,822 (225)

Analysis of Lotus japonicus nuclear pore NUP107-160 subcomplex mutants reveals pronounced structural plasticity and functional redundancy

Frontiers in Plant Science, 2014
Mutations in the Lotus japonicus nucleoporin genes, NUP85, NUP133 and NENA (SEH1), lead to defects in plant-microbe symbiotic signaling. The homologous proteins in yeast and vertebrates are part of the conserved NUP84/NUP107-160 sub-complex, which is an ...
Andreas eBinder, Martin eParniske
doaj   +1 more source

Crystal Structure of the N-Terminal Domain of Nup358/RanBP2 [PDF]

, 2012
Key steps in mRNA export are the nuclear assembly of messenger ribonucleoprotein particles (mRNPs), the translocation of mRNPs through the nuclear pore complex (NPC), and the mRNP remodeling events at the cytoplasmic side of the NPC.
Antonuk, C. Danielle, Blobel, Günter, Hoelz, André, Kassube, Susanne A., Lin, Daniel H., Napetschnig, Johanna, Stuwe, Tobias   +6 more
core  

Phosphorylation of ELYS promotes its interaction with VAPB at decondensing chromosomes during mitosis

EMBO Reports
ELYS is a nucleoporin that localizes to the nuclear side of the nuclear pore complex (NPC) in interphase cells. In mitosis, it serves as an assembly platform that interacts with chromatin and then with nucleoporin subcomplexes to initiate post-mitotic ...
Christina James, Ulrike Möller, Christiane Spillner, Sabine König, Olexandr Dybkov, Henning Urlaub, Christof Lenz, Ralph H Kehlenbach   +7 more
doaj   +1 more source

Nucleoporin 153 deficiency in adult neural stem cells defines a pathological protein-network signature and defective neurogenesis in a mouse model of AD

Stem Cell Research & Therapy
Background Reduction of adult hippocampal neurogenesis is an early critical event in Alzheimer’s disease (AD), contributing to progressive memory loss and cognitive decline.
Claudia Colussi, Alessia Bertozzi, Lucia Leone, Marco Rinaudo, Raimondo Sollazzo, Federica Conte, Elena Paccosi, Luca Nardella, Giuseppe Aceto, Domenica Donatella Li Puma, Cristian Ripoli, Maria Gabriella Vita, Camillo Marra, Marcello D’Ascenzo, Claudio Grassi   +14 more
doaj   +1 more source

Towards reconciling structure and function in the nuclear pore complex [PDF]

, 2018
The spatial separation between the cytoplasm and the cell nucleus necessitates the continuous exchange of macromolecular cargo across the double-membraned nuclear envelope.
Aebi, Ueli, Fahrenkrog, Birthe, Lim, Roderick   +2 more
core  

From the trap to the basket: getting to the bottom of the nuclear pore complex [PDF]

, 2018
Nuclear pore complexes (NPCs) are large supramolecular assemblies that perforate the double-membraned nuclear envelope and serve as the sole gateways of molecular exchange between the cytoplasm and the nucleus in interphase cells.
Aebi, Ueli, Lim, Roderick, Stoffler, Daniel   +2 more
core  

Multifunctional roles of Brl1-Brr6 in nuclear envelope fusion during nuclear pore complex biogenesis

The EMBO Journal
Brl1 and Brr6 are integral membrane proteins of the yeast nuclear envelope (NE) that transiently associate with nuclear pore complexes (NPCs). The exact roles of Brl1 and Brr6 during NPC assembly are unclear.
Sayan Mondal, Annett Neuner, Azqa Ajmal Khan, Jlenia Vitale, Elmar Schiebel   +4 more
doaj   +1 more source

Nucleoporin [PDF]

, 2020
openaire   +1 more source

Novel nucleoporin drives aggressiveness [PDF]

Nature Reviews Urology, 2018
openaire   +2 more sources

Population diversity validation for Alzheimer's disease "unifying" models. [PDF]

Alzheimers Dement
Rudroff T.
europepmc   +1 more source