Results 121 to 130 of about 14,867 (213)

Intramolecular Cohesion of Coils Mediated by Phenylalanine-Glycine Motifs in the Natively Unfolded Domain of a Nucleoporin [PDF]

open access: yes, 2008
The nuclear pore complex (NPC) provides the sole aqueous conduit for macromolecular exchange between the nucleus and the cytoplasm of cells. Its diffusion conduit contains a size-selective gate formed by a family of NPC proteins that feature large ...
Colvin, Michael E.   +6 more
core  

Nucleoporin 153 deficiency in adult neural stem cells defines a pathological protein-network signature and defective neurogenesis in a mouse model of AD

open access: yesStem Cell Research & Therapy
Background Reduction of adult hippocampal neurogenesis is an early critical event in Alzheimer’s disease (AD), contributing to progressive memory loss and cognitive decline.
Claudia Colussi   +14 more
doaj   +1 more source

The Nucleoporin RanBP2 Has SUMO1 E3 Ligase Activity

open access: yes, 2002
Posttranslational modification with SUMO1 regulates protein/protein interactions, localization, and stability. SUMOylation requires the E1 enzyme Aos1/Uba2 and the E2 enzyme Ubc9. A family of E3-like factors, PIAS proteins, was discovered recently.
Pichler, Andrea   +4 more
core   +1 more source

Crystal structure of the metazoan Nup62•Nup58•Nup54 nucleoporin complex.

open access: yes, 2015
Nuclear pore complexes (NPCs) conduct nucleocytoplasmic transport and gain transport selectivity through nucleoporin FG domains. Here, we report a structural analysis of the FG Nup62•58•54 complex, which is a crucial component of the transport system. It
Görlich, D.   +9 more
core   +1 more source

PhD

open access: yes, 2007
dissertationTrafficking events across the nuclear envelope (NE) require specific interactions between cargo-receptor complexes and proteins of the nuclear pore complex (NPC).
Ball, Jennifer R.
core  

A nucleoporin that facilitates meiotic kinetochore reorganization [PDF]

open access: yesCell Cycle, 2016
Hui-Ju, Yang   +2 more
openaire   +2 more sources

Nucleoporin 98 Rearrangements in Acute Leukemia: A Genomic Landscape Study. [PDF]

open access: yesHematol Oncol
Batayneh O   +10 more
europepmc   +1 more source

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